Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface
Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction...
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| Published in: | Functional Materials |
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| Date: | 2018 |
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| Format: | Article |
| Language: | English |
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НТК «Інститут монокристалів» НАН України
2018
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/157159 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862738818505900032 |
|---|---|
| author | Juan Wang Tuo Li Yahong Ma Zongcheng Miao |
| author_facet | Juan Wang Tuo Li Yahong Ma Zongcheng Miao |
| citation_txt | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. |
| collection | DSpace DC |
| container_title | Functional Materials |
| description | Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction between amphotericin B and biomembrane were studied by analysis of phase transition and thermodynamic properties of monolayers. The Na⁺ions may affect the molecular orientation of amphotericin B, and it depends on the concentration of sodium ions. Low concentration of Na⁺ ions has an opposite effect to high concentration of that. The results are helpful for obtaining some information on the influence mechanism in the level of sodium ions on the interaction between amphotericin B and biomembrane in the angle of physics.
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| first_indexed | 2025-12-07T20:05:45Z |
| format | Article |
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| id | nasplib_isofts_kiev_ua-123456789-157159 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1027-5495 |
| language | English |
| last_indexed | 2025-12-07T20:05:45Z |
| publishDate | 2018 |
| publisher | НТК «Інститут монокристалів» НАН України |
| record_format | dspace |
| spelling | Juan Wang Tuo Li Yahong Ma Zongcheng Miao 2019-06-19T16:33:26Z 2019-06-19T16:33:26Z 2018 Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface / Juan Wang, Tuo Li, Yahong Ma, Zongcheng Miao // Functional Materials. — 2018. — Т. 25, № 3. — С. 432-438. — Бібліогр.: 15 назв. — англ. 1027-5495 DOI:https://doi.org/10.15407/fm25.03.432 https://nasplib.isofts.kiev.ua/handle/123456789/157159 Amphotericin B is a widely used polyene antifungal drug for the treatment of deep fungal infections. This drug could cause pores on the cell membrane. In this work, we used the dipalmitoylphosphatidylcholine monolayer as the model of cell membrane in half. The influence of Na⁺ions on the interaction between amphotericin B and biomembrane were studied by analysis of phase transition and thermodynamic properties of monolayers. The Na⁺ions may affect the molecular orientation of amphotericin B, and it depends on the concentration of sodium ions. Low concentration of Na⁺ ions has an opposite effect to high concentration of that. The results are helpful for obtaining some information on the influence mechanism in the level of sodium ions on the interaction between amphotericin B and biomembrane in the angle of physics. en НТК «Інститут монокристалів» НАН України Functional Materials Characterization and properties Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface Article published earlier |
| spellingShingle | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface Juan Wang Tuo Li Yahong Ma Zongcheng Miao Characterization and properties |
| title | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_full | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_fullStr | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_full_unstemmed | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_short | Effects of different concentrations of sodium ions on the self-assembly of amphotericin B and DPPC at the air-water interface |
| title_sort | effects of different concentrations of sodium ions on the self-assembly of amphotericin b and dppc at the air-water interface |
| topic | Characterization and properties |
| topic_facet | Characterization and properties |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/157159 |
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