Proline rich regions of coenzyme A synthase α and β interact with SH3 domains of signaling proteins in vitro

• Published in: Біополімери і клітина
• Date: 2008
• ISSN: 0233-7657
• Main Authors: Breus, O.S., Panasyuk, G.G., Gout, I.T., Filonenko, V.V., Nemazanyy, I.O.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2008
• Subjects: Структура та функції біополімерів
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/157672
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Proline rich regions of coenzyme A synthase α and β interact with SH3 domains of signaling proteins in vitro / O.S. Breus, G.G. Panasyuk, I.T. Gout, V.V. Filonenko, I.O. Nemazanyy // Біополімери і клітина. — 2008. — Т. 24, № 2. — С. 123-128. — Бібліогр.: 16 назв. — англ.

Coenzyme A-synthases α and β (CoASy α and CoASy β ) contain proline rich regions which may bring them into complexes with SH3-domain containing proteins. To test whether CoASy isoforms can bind to SH3 domains we performed in vitro pull down experiments. It was found that CoASy β N-terminal extension...