Dephosphorylation of tuberous sclerosis complex 2 by serine/threonine protein phosphatase 5

• Published in: Біополімери і клітина
• Date: 2008
• Main Authors: Malanchuk, O.M., Palchevskyy, S.S., Filonenko, V.V.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2008
• Subjects: Короткі повідомлення
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/157679
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Dephosphorylation of tuberous sclerosis complex 2 by serine/threonine protein phosphatase 5 / O.M. Malanchuk, S.S. Palchevskyy, V.V. Filonenko // Біополімери і клітина. — 2008. — Т. 24, № 2. — С. 176-179. — Бібліогр.: 16 назв. — англ.

We report here for the first time specific interaction between tuberous sclerosis complex 2 (TSC2) and protein phosphatase 5 (PP5) in mammalian cells. We found that the interaction is stronger in exponentially growing and serum stimulated cells when compared to serum starved cells. In addition, we p...