The gene expression pattern as a tool for assessment of components of microenvironment and response to anti-cancer therapy of prostate tumors

• Date: 2019
• Main Authors: Gerashchenko, G.V., Chashchina, L.I., Rynditch, A.V., Kashuba, V.I.
• Format: Article
• Language: English
• Published: Видавничий дім "Академперіодика" НАН України 2019
• Series: Доповіді НАН України
• Subjects: Біологія
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/158098
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: The gene expression pattern as a tool for assessment of components of microenvironment and response to anti-cancer therapy of prostate tumors / G.V. Gerashchenko, L.I. Chashchina, A.V. Rynditch, V.I. Kashuba // Доповіді Національної академії наук України. — 2019. — № 4. — С. 86-93. — Бібліогр.: 15 назв. — англ.

We have analyzed the putative value of the pattern of relative expression (RE) of several genes that might be involved in a response to anti-cancer therapy, namely AR, PTEN, COX2, FASN, HMGCR, LDLR, and CTLA4, in samples of prostate adenoma, adenocarcinoma, and the paired conventional normal tissu...