In silico пошук gvp-кластерів Streptomyces globisporus 1912-2

• Published in: Фактори експериментальної еволюції організмів
• Date: 2015
• Main Author: Поліщук, Л.В.
• Format: Article
• Language: Ukrainian
• Published: Інститут молекулярної біології і генетики НАН України 2015
• Subjects: Аналіз та оцінка генетичних ресурсів
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/177548
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: НазваниеIn silico пошук gvp-кластерів Streptomyces globisporus 1912-2 / Л.В. Поліщук // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2015. — Т. 17. — С. 325-329. — Бібліогр.: 7 назв. — укр.

The aims – to find of gvp-clasters in the genome of S. globisporus 1912-2. Methods. The programs BLASTN were used for in silico analysis of the S. globisporus 1912-2 contigs library. Results. Two gvp-clusters in the library of S. globisporus 1912-2 chromosome fragments were found. One gvp-cluster was localized on Contig 264, the second cluster – on Contig 756 and Contig 781. Both gvp-clusters contain 10 genes in traditional order for streptomycetes cluster: gvpO - A - F - G - Y - Z - J - L - S - K. Conclusions. In silico analysis of the primary structures of two S. globisporus 1912-2 gvp-clusters did not find significant homology in their nucleotide sequences, therefore we could suggest that they were orthologous or significant changes in their primary structures occurred as a results of mutations after duplication. Keywords: Streptomyces globisporus 1912-2, gvp-claster, homology, chromosomal DNA.