От генетики человека до генной терапии – эволюция понятий и терминов, знаний и практик

• Published in: Фактори експериментальної еволюції організмів
• Date: 2016
• Main Authors: Пискун, Р.П., Савицкая, Е.А., Лилевская, А.А., Климчук, И.Н.
• Format: Article
• Language: Russian
• Published: Інститут молекулярної біології і генетики НАН України 2016
• Subjects: Генетика людини та медична генетика
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/177645
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: От генетики человека до генной терапии – эволюция понятий и терминов, знаний и практик / Р.П. Пискун, Е.А. Савицкая, А.А. Лилевская, И.Н. Климчук // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2016. — Т. 18. — С. 248-252. — Бібліогр.: 12 назв. — рос.

Aim. Genetics is developing so rapidly that not only the general public, but also experts do not have time to keep an eye
 on changes of our ideas of the fundamental basis of life and heredity. Methods. Research, evolutionary-historical and
 bibliographical methods have been used. Results. It became clear that the functional processes in a cell are incredibly
 complex. They become extremely difficult in the whole multicellular organism. In these processes involved many of
 variable components that interact with each other, and form a multidimentional spatiotemporal network. Therefore, the
 final effect can not be deduced by mechanical addition of components. Therefore some concepts and terms have been
 introduced to concretize the volume of knowledge and practical use of them in a particular field of genetics – the science
 of heredity and variation of all living organisms. Conclusions. For the last decades genetics and molecular biology have
 accumulated a huge volume of information, which requires not just understanding but also review of concepts, on which
 the principles of understanding organization of living systems are based.
 Keywords: human genetics, medical genetics, clinical genetics, cytogenetics, gene therapy.