Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912
The aim – to identify distribution of LndJ-like proteins among microorganisms and homology of their patterns. Method. Available Internet databases of information about primary structure of microbial DNAs and proteins on server NCBI were used. In silico analysis of Internet bases was done using avail...
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| Veröffentlicht in: | Фактори експериментальної еволюції організмів |
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| Datum: | 2013 |
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| Format: | Artikel |
| Sprache: | Russisch |
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Інститут молекулярної біології і генетики НАН України
2013
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 / Л.В. Полищук, В.В. Лукьянчук // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 88-92. — Бібліогр.: 2 назв. — рос. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862750143017648128 |
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| author | Полищук, Л.В. Лукьянчук, В.В. |
| author_facet | Полищук, Л.В. Лукьянчук, В.В. |
| citation_txt | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 / Л.В. Полищук, В.В. Лукьянчук // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 88-92. — Бібліогр.: 2 назв. — рос. |
| collection | DSpace DC |
| container_title | Фактори експериментальної еволюції організмів |
| description | The aim – to identify distribution of LndJ-like proteins among microorganisms and homology of their patterns. Method. Available Internet databases of information about primary structure of microbial DNAs and proteins on server NCBI were used. In silico analysis of Internet bases was done using available technical possibilities of program BLAST. The criterion for patterns selection was amino acid sequence of LndJ-protein of Streptomyces globisporus 1912. Results. Wide spreading of LndJ-homologous patterns among microorganisms of different taxonomic groups was detected, but the majority (97,6 %) is representatives of type Actinobacteria. The presence of LndJ-pattern orthologs with varying degree of homology (42 % to 95 %) was shown in 11 anguacyclines producing strains. Two of them each had two patterns for LndJ-paralogs (S. fradiae 2717 and Micromonospora sp. Tu6368). Strains S. antibioticus Tu6040 and S. globisporus 1912 each had (from 2 antiporters) only one ortholog of LndJ pattern. Conclusion. Antiporters with varying degrees of similarity to LndJ-protein are widespread among microorganisms as defense against their own antibiotics well as in ones that do not produce any biocides.

Key words: pattern, amino acid structure, homology, antiporter, resistance.
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| first_indexed | 2025-12-07T21:04:19Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-177712 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 2219-3782 |
| language | Russian |
| last_indexed | 2025-12-07T21:04:19Z |
| publishDate | 2013 |
| publisher | Інститут молекулярної біології і генетики НАН України |
| record_format | dspace |
| spelling | Полищук, Л.В. Лукьянчук, В.В. 2021-02-16T15:24:31Z 2021-02-16T15:24:31Z 2013 Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 / Л.В. Полищук, В.В. Лукьянчук // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 88-92. — Бібліогр.: 2 назв. — рос. 2219-3782 https://nasplib.isofts.kiev.ua/handle/123456789/177712 The aim – to identify distribution of LndJ-like proteins among microorganisms and homology of their patterns. Method. Available Internet databases of information about primary structure of microbial DNAs and proteins on server NCBI were used. In silico analysis of Internet bases was done using available technical possibilities of program BLAST. The criterion for patterns selection was amino acid sequence of LndJ-protein of Streptomyces globisporus 1912. Results. Wide spreading of LndJ-homologous patterns among microorganisms of different taxonomic groups was detected, but the majority (97,6 %) is representatives of type Actinobacteria. The presence of LndJ-pattern orthologs with varying degree of homology (42 % to 95 %) was shown in 11 anguacyclines producing strains. Two of them each had two patterns for LndJ-paralogs (S. fradiae 2717 and Micromonospora sp. Tu6368). Strains S. antibioticus Tu6040 and S. globisporus 1912 each had (from 2 antiporters) only one ortholog of LndJ pattern. Conclusion. Antiporters with varying degrees of similarity to LndJ-protein are widespread among microorganisms as defense against their own antibiotics well as in ones that do not produce any biocides.
 
 Key words: pattern, amino acid structure, homology, antiporter, resistance. ru Інститут молекулярної біології і генетики НАН України Фактори експериментальної еволюції організмів Аналіз та оцінка генетичних ресурсів Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 Search in silico for actinomycetes patterns which are homologous to LndJ-protein of Streptomyces globisporus 1912 Article published earlier |
| spellingShingle | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 Полищук, Л.В. Лукьянчук, В.В. Аналіз та оцінка генетичних ресурсів |
| title | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 |
| title_alt | Search in silico for actinomycetes patterns which are homologous to LndJ-protein of Streptomyces globisporus 1912 |
| title_full | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 |
| title_fullStr | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 |
| title_full_unstemmed | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 |
| title_short | Поиск in silico у актиномицетов паттернов, гомологичных LndJ-белку Streptomyces globisporus 1912 |
| title_sort | поиск in silico у актиномицетов паттернов, гомологичных lndj-белку streptomyces globisporus 1912 |
| topic | Аналіз та оцінка генетичних ресурсів |
| topic_facet | Аналіз та оцінка генетичних ресурсів |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/177712 |
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