Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы
Aims. To compare the genetic diversity of the Ukrainian regions by the Y-chromosome haplogroups, which are the high effective genetic markers for similar populations. Methods. The genotyping of Y-chromosome markers. Multivariate statistical analysis, correlation analysis. Results. The spectrum and f...
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| Опубліковано в: : | Фактори експериментальної еволюції організмів |
|---|---|
| Дата: | 2013 |
| Автори: | , , , , , , , |
| Формат: | Стаття |
| Мова: | Російська |
| Опубліковано: |
Інститут молекулярної біології і генетики НАН України
2013
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| Теми: | |
| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/178002 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы / О.М. Утевская, А.Т. Агджоян, А.С. Пшеничнов, Х.Д. Дибирова, М.И. Чухряева, Л.А. Атраментова, Е.В. Балановская, О.П. Балановский // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 338-341. — Бібліогр.: 6 назв. — рос. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1860141095343620096 |
|---|---|
| author | Утевская, О.М. Агджоян, А.Т. Пшеничнов, А.С. Дибирова, Х.Д. Чухряева, М.И. Атраментова, Л.А. Балановская, Е.В. Балановский, О.П. |
| author_facet | Утевская, О.М. Агджоян, А.Т. Пшеничнов, А.С. Дибирова, Х.Д. Чухряева, М.И. Атраментова, Л.А. Балановская, Е.В. Балановский, О.П. |
| citation_txt | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы / О.М. Утевская, А.Т. Агджоян, А.С. Пшеничнов, Х.Д. Дибирова, М.И. Чухряева, Л.А. Атраментова, Е.В. Балановская, О.П. Балановский // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 338-341. — Бібліогр.: 6 назв. — рос. |
| collection | DSpace DC |
| container_title | Фактори експериментальної еволюції організмів |
| description | Aims. To compare the genetic diversity of the Ukrainian regions by the Y-chromosome haplogroups, which are the high effective genetic markers for similar populations. Methods. The genotyping of Y-chromosome markers. Multivariate statistical analysis, correlation analysis. Results. The spectrum and frequency of Y chromosome haplogroups in the Ukrainian populations correspond to the genetic pattern of Eastern Europe. The frequency distribution of Y-chromosome haplogroups in different Ukrainian populations are similar. The genetic similarity of Ukrainian population or difference between them is not determined by the geographical distance. Conclusions. Ukrainian population belonging to different historical and territorial associations are homogeneous for Y-chromosome markers and have a higher genetic similarity to each other than to the neighboring ethnic groups.

Key words: Y-chromosome, haplogroup, Ukrainians, population, gene pool.
|
| first_indexed | 2025-12-07T17:49:32Z |
| format | Article |
| fulltext |
338
associated with HIV-1 disease. associated with a delayed progression to disease. The aim of this study was to
determine the frequency of chemokine receptor gene mutation CCR2-64I in people from Western region of
Ukraine. Methods. DNA from the above samples was isolated using a modified salting out method. Ex-
tracted DNA was amplified by Polymerase chain reaction (PCR). The PCR products were subsequently di-
gested with the restriction enzyme Bse8 I and subjected to electrophoresis in a 2 % agarose gel.
Results. A molecular genetic study of chemokine receptor gene mutation CCR2-64I performed in 147 people
from Western region of Ukraine. The frequency of CCR2-64I heterozygote was 12.92 % and the frequency
of CCR2-64I homozygous was 1.36 % n the studied group. CCR2-64I mutation were more frequently in
group of women (16.9 %) than in group of men (8.6 %). Conclusions. The results show relatively high ge-
netic resistance to HIV infection in people from Western region of Ukraine.
Key words: HIV infection, chemokine receptor, mutation.
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UTEVSKA . . 1,2, AGDZHOYAN A.T. 3,2, PSHENICHNOV A.S. 2, DIBIROVA KH. D. 2, 3,
CHUHRYAEVA M.I. 3, ATRAMENTOVA L.A. 1, BALANOVSKA E.V. 2, BALANOVSKY O.P. 2,3
1 V.N. Karazin Kharkiv National University
Ukraine, 61022, Kharkiv, Svoboda sq., 4, e-mail: outevsk@yandex.ru
2 Research Centre of Medical Genetics of the Russian Academy of Medical Sciences
Russia, Moscow
3 Vavilov Institute for General Genetics, Russian Academy of Sciences
Russia, Moscow
SIMILARITY OF UKRAINIAN POPULATIONS FROM DIFFERENT REGIONS REVEALED BY
Y-CHROMOSOMAL MARKERS
Aims. To compare the genetic diversity of the Ukrainian regions by the Y-chromosome haplogroups, which
are the high effective genetic markers for similar populations. Methods. The genotyping of Y-chromosome
markers. Multivariate statistical analysis, correlation analysis. Results. The spectrum and frequency of Y
chromosome haplogroups in the Ukrainian populations correspond to the genetic pattern of Eastern Europe.
The frequency distribution of Y-chromosome haplogroups in different Ukrainian populations are similar.
The genetic similarity of Ukrainian population or difference between them is not determined by the
geographical distance. Conclusions. Ukrainian population belonging to different historical and territorial
associations are homogeneous for Y-chromosome markers and have a higher genetic similarity to each other
than to the neighboring ethnic groups.
Key words: Y-chromosome, haplogroup, Ukrainians, population, gene pool.
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|
| id | nasplib_isofts_kiev_ua-123456789-178002 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 2219-3782 |
| language | Russian |
| last_indexed | 2025-12-07T17:49:32Z |
| publishDate | 2013 |
| publisher | Інститут молекулярної біології і генетики НАН України |
| record_format | dspace |
| spelling | Утевская, О.М. Агджоян, А.Т. Пшеничнов, А.С. Дибирова, Х.Д. Чухряева, М.И. Атраментова, Л.А. Балановская, Е.В. Балановский, О.П. 2021-02-17T15:48:16Z 2021-02-17T15:48:16Z 2013 Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы / О.М. Утевская, А.Т. Агджоян, А.С. Пшеничнов, Х.Д. Дибирова, М.И. Чухряева, Л.А. Атраментова, Е.В. Балановская, О.П. Балановский // Фактори експериментальної еволюції організмів: Зб. наук. пр. — 2013. — Т. 13. — С. 338-341. — Бібліогр.: 6 назв. — рос. 2219-3782 https://nasplib.isofts.kiev.ua/handle/123456789/178002 Aims. To compare the genetic diversity of the Ukrainian regions by the Y-chromosome haplogroups, which are the high effective genetic markers for similar populations. Methods. The genotyping of Y-chromosome markers. Multivariate statistical analysis, correlation analysis. Results. The spectrum and frequency of Y chromosome haplogroups in the Ukrainian populations correspond to the genetic pattern of Eastern Europe. The frequency distribution of Y-chromosome haplogroups in different Ukrainian populations are similar. The genetic similarity of Ukrainian population or difference between them is not determined by the geographical distance. Conclusions. Ukrainian population belonging to different historical and territorial associations are homogeneous for Y-chromosome markers and have a higher genetic similarity to each other than to the neighboring ethnic groups.
 
 Key words: Y-chromosome, haplogroup, Ukrainians, population, gene pool. ru Інститут молекулярної біології і генетики НАН України Фактори експериментальної еволюції організмів Генетика людини та медична генетика Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы Similarity of ukrainian populations from different regions revealed by Y-chromosomal markers Article published earlier |
| spellingShingle | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы Утевская, О.М. Агджоян, А.Т. Пшеничнов, А.С. Дибирова, Х.Д. Чухряева, М.И. Атраментова, Л.А. Балановская, Е.В. Балановский, О.П. Генетика людини та медична генетика |
| title | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы |
| title_alt | Similarity of ukrainian populations from different regions revealed by Y-chromosomal markers |
| title_full | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы |
| title_fullStr | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы |
| title_full_unstemmed | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы |
| title_short | Сходство украинских популяций из различных территориальных подразделений по маркерам Y-хромосомы |
| title_sort | сходство украинских популяций из различных территориальных подразделений по маркерам y-хромосомы |
| topic | Генетика людини та медична генетика |
| topic_facet | Генетика людини та медична генетика |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/178002 |
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