Interaction of 4-substituted 5-carbethoxy-6-chloromethylpyrimidin-2-ones with hydrazines and hydrazide derivatives: synthesis and structure

• Published in: Украинский химический журнал
• Date: 2010
• ISSN: 0041–6045
• Main Authors: Lebedyeva, І.О., Povstyanoy, М.V., Povstyanoy, V.М., Ryabitskii, A.B., Panasyuk, O.G.
• Format: Article
• Language: English
• Published: Інститут загальної та неорганічної хімії ім. В.І. Вернадського НАН України 2010
• Subjects: Органическая химия
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/185945
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Interaction of 4-substituted 5-carbethoxy-6-chloromethylpyrimidin-2-ones with hydrazines and hydrazide derivatives: synthesis and structure / І.О. Lebedyeva, М.V. Povstyanoy, V.М. Povstyanoy, A.B. Ryabitskii, O.G. Panasyuk // Украинский химический журнал. — 2010. — Т. 76, № 3. — С. 46-55. — Бібліогр.: 9 назв. — рос.

Reaction of 5-carbethoxy-6-chloromethyl-3,4-dihydropyrimidin-2(1H)-ones with N,N’-binucleophiles has been studied on hydrazine hydrate, monosubstituted hydrazines and carboxylic acid hydrazides. It has been determined that the reaction takes place as nucleophilic substitution of halogen on N,N’-binu...