Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University
The creation of a PET center in the Kharkov region is proposed. This is facilitated by the transfer of the cyclotron by the Julich Research Center (Germany) to Kharkiv, which will ensure the development of the diagnostic radiopharmaceutical “Glucose,¹⁸F”. An additional expansion of the treatment bas...
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| Опубліковано в: : | Вопросы атомной науки и техники |
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Національний науковий центр «Харківський фізико-технічний інститут» НАН України
2020
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| Цитувати: | Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University / V.O. Voronko, R.N. Dronov, B.I. Shramenko, І.V. Beloziorov, I.O. Girka // Problems of atomic science and tecnology. — 2020. — № 3. — С. 168-171. — Бібліогр.: 9 назв. — англ. |
Репозитарії
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Voronko, V.O. Dronov, R.N. Shramenko, B.I. Beloziorov, І.V. Girka, I.O. 2023-11-27T13:42:23Z 2023-11-27T13:42:23Z 2020 Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University / V.O. Voronko, R.N. Dronov, B.I. Shramenko, І.V. Beloziorov, I.O. Girka // Problems of atomic science and tecnology. — 2020. — № 3. — С. 168-171. — Бібліогр.: 9 назв. — англ. 1562-6016 PACS: 87.57.uk, 87.57.un https://nasplib.isofts.kiev.ua/handle/123456789/194549 The creation of a PET center in the Kharkov region is proposed. This is facilitated by the transfer of the cyclotron by the Julich Research Center (Germany) to Kharkiv, which will ensure the development of the diagnostic radiopharmaceutical “Glucose,¹⁸F”. An additional expansion of the treatment base is possible by acquiring a microtron electron accelerator, which will make it possible to produce and use for treatment of cancer the “Ethanol,¹¹C” radio-pharmaceutical and the “Glucose,¹¹C” diagnostic radiopharmaceutical developed at the NSC KIPT. Запропоновано створення в Харківському регіоні ПЕТ-центру. Цьому сприяє передача Юліхським науковим центром (Німеччина) у м. Харків циклотрона, який забезпечить напрацювання діагностичного радіофармпрепарата «Глюкоза,¹⁸F». Додаткове розширення лікувальної бази можливо шляхом придбання прискорювача електронів мікротрона, який дасть можливість виробляти і використовувати для лікування раку радіофармпрепарат «Етанол,¹¹С», а також діагностичний радіофармпрепарат «Глюкоза,¹¹С», розроблені в ННЦ ХФТІ. Предложено создание в Харьковском регионе ПЭТ-центра. Этому способствует передача Юлихским научным центром (Германия) в г. Харькове циклотрона, который обеспечит наработку диагностического радиофармпрепарата «Глюкоза,¹⁸F». Дополнительное расширение лечебной базы возможно путем приобретения ускорителя электронов микротрона, который даст возможность производить и использовать для лечения рака радиофармпрепарат «Этанол,¹¹С», а также диагностический радиофармпрепарат «Глюказа,¹¹С», разработанные в ННЦ ХФТИ. The authors express their sincere thanks for the assistance and helpful comments when discussing the Proposal to: M.F. Shulga - Director General of NSC KIPT NAS; M.V. Krasnoselsky - Director of Grigoriev Institute for Medical Radiology; V.P. Starenky - Head of the Department of Radiation Therapy of Grigoriev Institute for Medical Radiology; M.V. Kolomensky - Head of Kharkiv Specialized Medical Unit № 13; V.G. Rudichev - Leading researcher of the School of Physics and Technology of KhNU. en Національний науковий центр «Харківський фізико-технічний інститут» НАН України Вопросы атомной науки и техники Application of accelerators in radiation technologies Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University Пропозиція зі створення центру позитрон-емісійної томографії на базі медичного та фізико-технічного факультетів ХНУ Предложение по созданию центра позитрон-эмиссионной томографии на базе медицинского и физико-технического факультетов ХНУ Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University |
| spellingShingle |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University Voronko, V.O. Dronov, R.N. Shramenko, B.I. Beloziorov, І.V. Girka, I.O. Application of accelerators in radiation technologies |
| title_short |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University |
| title_full |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University |
| title_fullStr |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University |
| title_full_unstemmed |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University |
| title_sort |
proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of kharkiv national university |
| author |
Voronko, V.O. Dronov, R.N. Shramenko, B.I. Beloziorov, І.V. Girka, I.O. |
| author_facet |
Voronko, V.O. Dronov, R.N. Shramenko, B.I. Beloziorov, І.V. Girka, I.O. |
| topic |
Application of accelerators in radiation technologies |
| topic_facet |
Application of accelerators in radiation technologies |
| publishDate |
2020 |
| language |
English |
| container_title |
Вопросы атомной науки и техники |
| publisher |
Національний науковий центр «Харківський фізико-технічний інститут» НАН України |
| format |
Article |
| title_alt |
Пропозиція зі створення центру позитрон-емісійної томографії на базі медичного та фізико-технічного факультетів ХНУ Предложение по созданию центра позитрон-эмиссионной томографии на базе медицинского и физико-технического факультетов ХНУ |
| description |
The creation of a PET center in the Kharkov region is proposed. This is facilitated by the transfer of the cyclotron by the Julich Research Center (Germany) to Kharkiv, which will ensure the development of the diagnostic radiopharmaceutical “Glucose,¹⁸F”. An additional expansion of the treatment base is possible by acquiring a microtron electron accelerator, which will make it possible to produce and use for treatment of cancer the “Ethanol,¹¹C” radio-pharmaceutical and the “Glucose,¹¹C” diagnostic radiopharmaceutical developed at the NSC KIPT.
Запропоновано створення в Харківському регіоні ПЕТ-центру. Цьому сприяє передача Юліхським науковим центром (Німеччина) у м. Харків циклотрона, який забезпечить напрацювання діагностичного радіофармпрепарата «Глюкоза,¹⁸F». Додаткове розширення лікувальної бази можливо шляхом придбання прискорювача електронів мікротрона, який дасть можливість виробляти і використовувати для лікування раку радіофармпрепарат «Етанол,¹¹С», а також діагностичний радіофармпрепарат «Глюкоза,¹¹С», розроблені в ННЦ ХФТІ.
Предложено создание в Харьковском регионе ПЭТ-центра. Этому способствует передача Юлихским научным центром (Германия) в г. Харькове циклотрона, который обеспечит наработку диагностического радиофармпрепарата «Глюкоза,¹⁸F». Дополнительное расширение лечебной базы возможно путем приобретения ускорителя электронов микротрона, который даст возможность производить и использовать для лечения рака радиофармпрепарат «Этанол,¹¹С», а также диагностический радиофармпрепарат «Глюказа,¹¹С», разработанные в ННЦ ХФТИ.
|
| issn |
1562-6016 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/194549 |
| citation_txt |
Proposal for creation of positron-emission tomography center on the basis of school of medicine and school of physics and technology of Kharkiv National University / V.O. Voronko, R.N. Dronov, B.I. Shramenko, І.V. Beloziorov, I.O. Girka // Problems of atomic science and tecnology. — 2020. — № 3. — С. 168-171. — Бібліогр.: 9 назв. — англ. |
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ISSN 1562-6016. ВАНТ. 2020. №3(127) 168
APPLICATION OF ACCELERATORS IN RADIATION TECHNOLOGIES
PROPOSAL FOR CREATION OF POSITRON-EMISSION
TOMOGRAPHY CENTER ON THE BASIS OF SCHOOL OF MEDICINE
AND SCHOOL OF PHYSICS AND TECHNOLOGY OF KHARKIV
NATIONAL UNIVERSITY
V.O. Voronko1, R.N. Dronov1, B.I. Shramenko1, І.V. Beloziorov2, I.O. Girka2
1National Science Center “Kharkov Institute of Physics and Technology”, Kharkiv, Ukraine;
2V.N. Karazin Kharkiv National University, Kharkiv, Ukraine
E-mail: bshram@kipt.kharkov.ua
The creation of a PET center in the Kharkov region is proposed. This is facilitated by the transfer of the cyclo-
tron by the Julich Research Center (Germany) to Kharkiv, which will ensure the development of the diagnostic ra-
diopharmaceutical “Glucose,18F”. An additional expansion of the treatment base is possible by acquiring a microtron
electron accelerator, which will make it possible to produce and use for treatment of cancer the “Ethanol,11C” radio-
pharmaceutical and the "Glucose,11C" diagnostic radiopharmaceutical developed at the NSC KIPT.
PACS: 87.57.uk, 87.57.un
INTRODUCTION
The proposal is an updated version of the Project [1]
that was proposed earlier and has not been implemented
due to the lack of radiopharmaceuticals for PET diag-
nostics and the PET tomograph itself. Given the ab-
sence of such a Center in the Kharkiv region, the need
to create a Center for Positron Emission Tomography
has not only lost its relevance, but has become even
more urgent. At present, the situation with radiophar-
maceuticals for PET diagnostics has been improved due
to production in NSC KIPT of ready to use radiophar-
maceuticals labeled with the 11C isotope: “Glucose,11C”
[2, 9], and “Ethanol,11C” [3].
The 11C, 13N, 15O, and 18F isotopes, which form the
basis of radiopharmaceuticals for PET diagnostics, have
short half-lives: from 2 min (15O) to 110 min (18F). For
this reason, the main condition for the implementation
of the Proposal is the need to locate the PET in the im-
mediate vicinity of the isotope and radiopharmaceutical
production site.
ESSENCE OF PROPOSAL
The condition of close proximity of accelerators
where pharmaceuticals produced and PET scanner,
where pharmaceuticals is used, is well met by this pro-
posal. According to proposal, accelerators, which are
used to obtain the pharmaceuticals labeled with 11C and
18F isotopes, will be placed in a building that belongs to
school of physics and technology of Kharkiv National
University. The PET is planned to be placed in the
building of Kharkiv Specialized Medical Unit № 13,
which is only 134 meters away (in the line of sight). The
production of 18F isotopes, “Fludeoxyglucose,18F” will
be performed on the accelerator of protons (cyclotron)
and isotopes 11C (radiopharmaceuticals “Glucose,11C”
[2, 9] and “Ethanol,11C” [3]) will be produced on elec-
tron accelerator microtron MM50 Scanditronix.
This will allow for the rapid transportation of the
generated isotopes from the accelerator to the PET using
pneumatic tube system (PTS) (Fig. 1).
Fig. 1. Schematic location of the available buildings
involved in Proposition:
1 Building of KhNU’s School of Physics and Technol-
ogy; 2 Vault; 7 m below ground level where accelera-
tors (cyclotron/microtron) should be installed;
3 Place where ampoule (A) with isotopes or radio-
pharmaceutical is loaded into the PTS; 4 Place near
the PET where ampoule (A) is unloaded from PTS for
final preparation of radiopharmaceutical (if necessary);
5 PET; 6 Building for PET and patient care rooms
Transport of the ampoule (A) between positions 3
and 4 to a distance of 134 m is accomplished by pneu-
matic tube system and takes approximately one minute.
The aerial view of the available buildings involved is
shown in Fig. 2.
One of the important factors that will contribute to
the implementation of the Proposal is the successful
implementation in practice of NSC KIPT the possibility
of obtaining new radiopharmaceuticals labeled with 11C
isotope ready for use for PET diagnosis and treatment.
The development of new radiopharmaceuticals is de-
scribed in patent applications [2, 3] and radiopharma-
ceutical “Glucose,11C” in [9] correspondingly.
It is important that the invention [3] significantly
improve the method proposed by American scientists in
the treatment of cancer with ethanol (alcohol) [4, 5].
These researchers believe that even one injection of
ethanol-based gel can cure certain types of tumors, and
that some cancers of the cervix and breast cancer can be
treated.
ISSN 1562-6016. ВАНТ. 2020. №3(127) 169
Fig. 2. The aerial view of the buildings involved
in Proposition (Source: Google Maps).
1 Building of KhNU`s School of Physics and Technol-
ogy; 2 Main building of Kharkiv Specialized Medical
Unit № 13; 3 Building for PET and patient care rooms
Our improvement in cancer treatment [4, 5] consists
of the labeling of ethyl alcohol with 11C isotope (i.e., the
creation of a new radiopharmaceutical “Ethanol,11C”
[3]), which enables PET imaging to visualize the loca-
tion and spatial shape of the ethanol introduced into the
tumor. The use of “Ethanol,11C” provides continuous
dynamic control over the cancer treatment process with
ethanol and the possibility of additional corrective injec-
tions of ethanol, if necessary.
The timely implementation of the Proposal will open
wide opportunities for cancer treatment in Ukraine
without a significant time gap from the US.
As the new method of treating cancer with ethanol
[4, 5] is only beginning to develop, the timely imple-
mentation of the Proposal will help close the huge gap
that exists today between cancer treatment options in
Ukraine and in developed countries.
In addition, the implementation of the Proposal (as a
pilot version) will make it possible to test in practice the
efficiency and effectiveness of the complexes of the PET
diagnostic system, their functionality and the correctness
of the conceptual approaches that underlie the Proposal,
in order to take into account the acquired experience for
further improvement, development of PET cancer
treatment centers in Ukraine.
The implementation of the Proposal includes two
stages:
STAGE I (Year 2021)
Provides PET diagnostics with the use of “Flude-
oxyglucose,18F” obtained on a proton accelerator, a cy-
clotron, using well-developed (licensed) worldwide
technology.
1. Installation and commissioning of cyclotron (baby
cyclotron)*. Building 1 (vault 2) (see Fig. 1).
2. Design and construction of the pneumatic tube
system (see Fig. 1).
3. Installation of PET** in Building 6 (see Fig. 1),
(Building 3 (see Fig. 2).
4. Development of complex functioning PET di-
agnostic center.
*Cyclotron will be delivered from the Jülich Science
Center (Germany) according to an existing agreement.
**Obtaining PET from structures interested in the
use of radiopharmaceuticals that will be based on a cy-
clotron (under existing arrangement), or purchasing a
PET following the example of a PET center in Kyiv
(Feofaniya).
STAGE II (Years 2021-2022)
Provides practical implementation of the method of
cancer treatment with ethanol by the method [4, 5] tak-
ing into account improvements [3] (“Ethanol,11C”), as
well as the provision of PET diagnostics, using the tra-
ditional radiopharmaceutical “Fludeoxyglucose,18F” and
the new radiopharmaceutical “Glucose,11C” [2, 9],
which provides receptor (repeat) studies. Glucose,11C
and Ethanol,11C will be developed on the MM-50
(Scanditronix)*** electron microtron accelerator, which
is selected as an electron source due to its reliability and
ease of use (in addition, a microtron is cheaper than a
linear accelerator).
1. Installation and commissioning MM-50 microtron
with 30…50 MeV energy and average current of
10…20 µA.
2. Practical preparation and use of the pharmaceuti-
cal “Ethanol,11C” [3] for the treatment of cancer with
ethanol by the method [4, 5] in combination with PET
diagnostics.
3. Practical preparation and use of the pharmaceuti-
cal “Glucose,11C” [2, 9] for PET diagnostics, including
frequently repetitive studies using PET.
***The acquisition of the MM-50 microtron (Scan-
ditronix) overseas is planned.
Factors that will contribute to the implementation of
the Proposal:
- the specialized vault of the KhNU, where accelera-
tors are to be installed, has all the relevant permits for
operating the accelerators in the modes planned by this
Proposal;
- the use of existing buildings for PET and accelera-
tors significantly reduces the timeframe for the imple-
mentation of the Proposal;
- the location of the PET in close proximity to the
isotope production site greatly simplifies its implemen-
tation and, most importantly, enables it to maintain the
accumulated level of ultra short lived isotope`s activity
by transporting it via pneumatic tube system to the ra-
diopharmaceutical preparation site (near PET);
- the availability of qualified personnel of
NSC KIPT and those of School of Physics and Tech-
nology of the KhNU, whose participation will ensure
the implementation of the Proposal, will help to ensure
the constant development of isotopes 18F and 11C and
preparation of radiopharmaceutical based on them for
PET diagnosis and treatment [2, 3, 6 - 9];
- participation of medical staff of the Grigoriev Insti-
tute for Medical Radiology (as provided by the Pro-
posal), who has experience in the field of nuclear medi-
cine, with additional involvement in the practice and
work of students of the School of Medicine, as well as
the Department of Nuclear and Medical Physics of the
School of Physics and Technology of KhNU;
- an important factor that will contribute to the im-
plementation of the proposal for the creation of the Cen-
ter (as an additional training base) may be the training
of young people at the School of Physics and Technol-
ISSN 1562-6016. ВАНТ. 2020. №3(127) 170
ogy of KhNU under the already accredited educational
program “Medical Physics”;
- the availability of proven methods of obtaining ra-
diopharmaceuticals “Glucose,11C” and “Ethanol,11C” on
the electron accelerator of the NSC KhIPT [2, 3, 9].
Executing organizations to be involved in the im-
plementation of the Proposal:
1. National Science Center “Kharkov Institute of
Physics and Technology”.
2. Karazin Kharkiv National University. (School of
Physics and Technology, School of Medicine).
3. Grigoriev Institute for Medical Radiology.
CONCLUSIONS
1. Implementation of Stage I of the Proposal will
give the opportunity to provide Kharkiv region with a
standard Center for PET diagnostics. Under favorable
conditions (free delivery of cyclotron (baby cyclotron)
and PET tomograph), the cost of Stage I will be deter-
mined only by the cost of licensed technology of crea-
tion of radiopharmaceutical “Fludeoxyglucose,18F” and
the cost of construction of the pneumatic tube system.
For this reason, Stage I takes relatively modest funding
and deserves careful attention.
2. The implementation of Stage II will create the
world's first, unique PET Center with the possibility of
treating cancer with the new radiopharmaceutical “Eth-
anol,11C” [3], which was developed by NSC KIPT after
research by the American researchers on cancer treat-
ment using conventional ethanol [4, 5]. The cost of this
stage will be determined by the cost of the MM-50 mi-
crotron (Scanditronix).
3. The fulfillment of the Proposal does not require
costly and long-term capital construction of buildings
for PET and accelerators, which significantly shortens
the Proposal`s implementation time.
4. The complementary nature of the above factors,
including the territorial proximity, administrative and
organizational subordination of Proposal`s participants,
as well as the scientific and ideological interest of scien-
tific and medical institutions in achieving the ultimate
goal, will contribute to the practical implementation of
this Proposal.
ACKNOWLEDGEMENT
The authors express their sincere thanks for the as-
sistance and helpful comments when discussing the
Proposal to:
M.F. Shulga Director General of NSC KIPT NAS;
M.V. Krasnoselsky Director of Grigoriev Institute
for Medical Radiology;
V.P. Starenky Head of the Department of Radia-
tion Therapy of Grigoriev Institute for Medical Radiol-
ogy;
M.V. Kolomensky Head of Kharkiv Specialized
Medical Unit № 13;
V.G. Rudichev Leading researcher of the School
of Physics and Technology of KhNU.
REFERENCES
1. A.M. Dovbnya, M.P. Dykyy, A.S. Zadvornyy,
O.H. Konovalov, M.I. Pylypenko, P.V Sorokin,
B.I. Shramenko. Proekt Pivnichno-Skhidnoho re-
hionalnoho Tsentru pozytron-emisiynoyi to-
mohrafiyi // URZH. 1999, № 7, p. 316-317 (in
Ukrainian).
2. A.M. Dovbnya, B.I. Shramenko. Sposib oderz-
hannya radiofarmpreparatu «Hlyukoza, 11C» dlya
diahnostyky iz zastosuvannya pozytron-emisiynoyi
tomohrafiyi. Patent Ukrayiny № 118509 vid
25.01.2019 r. (in Ukrainian).
3. A.M. Dovbnya, B.I. Shramenko. Radiofarmpreparat
z izotopom 11C ta sposib yoho otrymannya. Patent
Ukrayiny № 120321.vid 11.11.2019 r. (in Ukrain-
ian).
4. Markus Schober, and Elaine Fuchs, Rockefeller
University. New Low-Cost Cancer Treatment Could
Kill Tumors With Ethanol // Nature Scientific Re-
ports, Sept. 2017. (https://futurism.com/ new-low-
cost-cancer-treatment-could-kill-tumors-with-
ethanol/).
5. R. Morhard, et al. Development of enhanced ethanol
ablation as an alternative to surgery in treatment of
superficial solid tumors // Scientific Reports 7, Arti-
cle number 8750. Published:18-Aug-
2017.doi:10.1038/s41598-017-09371-2 PMCID:
PMC5562881 PMID: 28821832.
6. M.I. Ayzatskyy, Ye.Z. Biller, V.N. Boryskin,
M.P. Dykyy, B.I. Shramenko ta inshi. Rozrobka v
NSC KIPT fotoyadernoyi tekhnolohiyi vyrobnytstva
medychnykh radionuklidiv // URZH. 2007, № 2,
p. 221-223 (in Ukrainian).
7. M.I. Ayzatskyy, N.P. Dykyy, A.N. Dovbnya,
Yu.V. Lyashko y dr. Oderzhannya Cu-67 bez nosiya
na pryskoryuvachi elektroniv // URZH. 2007, № 2,
p. 223-227 (in Ukrainian).
8. A.I. Azarov, A.N. Dovbnya, M.A. Dolzhec, et al.
Аbout the use in nuclear medicine of pharmaceuti-
cals on the basis of the isotope 18F and its achieve-
ments on linear electron accelerators of NIK “Аccel-
erator” // Problems of Atomic Science and Technol-
ogy. Series “Nuclear Physics Investigations”. 2017,
№ 6, p. 133-136.
9. А.N. Dovbnya, R.N. Dronov, V.A. Kushnir, et al.
Production of 11C and 18F isotopes. Getting the
“Glucose,11C” radiopharmaceutical // East European
Journal of Physics (EEJP). 2018, v. 5, № 4, p. 77-
86.
Article received 28.02.2020
ISSN 1562-6016. ВАНТ. 2020. №3(127) 171
ПРЕДЛОЖЕНИЕ ПО СОЗДАНИЮ ЦЕНТРА ПОЗИТРОН-ЭМИССИОННОЙ ТОМОГРАФИИ
НА БАЗЕ МЕДИЦИНСКОГО И ФИЗИКО-ТЕХНИЧЕСКОГО ФАКУЛЬТЕТОВ ХНУ
В.А. Воронко, Р.Н. Дронов, Б.И. Шраменко, И.В. Белозёров, И.А. Гирка
Предложено создание в Харьковском регионе ПЭТ-центра. Этому способствует передача Юлихским на-
учным центром (Германия) в г. Харькове циклотрона, который обеспечит наработку диагностического ра-
диофармпрепарата «Глюкоза,18 F». Дополнительное расширение лечебной базы возможно путем приобрете-
ния ускорителя электронов микротрона, который даст возможность производить и использовать для лечения
рака радиофармпрепарат «Этанол,11С», а также диагностический радиофармпрепарат «Глюказа,11С», разра-
ботанные в ННЦ ХФТИ.
ПРОПОЗИЦІЯ ЗІ СТВОРЕННЯ ЦЕНТРУ ПОЗИТРОН-ЕМІСІЙНОЇ ТОМОГРАФІЇ
НА БАЗІ МЕДИЧНОГО ТА ФІЗИКО-ТЕХНІЧНОГО ФАКУЛЬТЕТІВ ХНУ
В.О. Воронко, Р.М. Дронов, Б.І. Шраменко, І.В. Белозьоров, І.О. Гірка
Запропоновано створення в Харківському регіоні ПЕТ-центру. Цьому сприяє передача Юліхським нау-
ковим центром (Німеччина) у м. Харків циклотрона, який забезпечить напрацювання діагностичного радіо-
фармпрепарата «Глюкоза,18F». Додаткове розширення лікувальної бази можливо шляхом придбання при-
скорювача електронів мікротрона, який дасть можливість виробляти і використовувати для лікування раку
радіофармпрепарат «Етанол,11С», а також діагностичний радіофармпрепарат «Глюкоза,11С», розроблені в
ННЦ ХФТІ.
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