Note about Cholesterol

A translation from German of the original paper by Prof. Planer in which he describes his observations of selective light reflection in monotropic cholesteric liquid crystal phase of cholesteryl chloride that he synthesized. Translation by Peter Oelschlaeger, Chemistry Department and Center for Macr...

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Veröffentlicht in:Condensed Matter Physics
Datum:2010
1. Verfasser: Planer, J.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут фізики конденсованих систем НАН України 2010
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/32112
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Zitieren:Note about Cholesterol / J. Planer // Condensed Matter Physics. — 2010. — Т. 13, № 3. — С. 37001:1-2. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-32112
record_format dspace
spelling Planer, J.
2012-04-08T19:31:56Z
2012-04-08T19:31:56Z
2010
Note about Cholesterol / J. Planer // Condensed Matter Physics. — 2010. — Т. 13, № 3. — С. 37001:1-2. — англ.
1607-324X
PACS: 61.30.-v, 64.70.pv, 82.70.Dd
https://nasplib.isofts.kiev.ua/handle/123456789/32112
A translation from German of the original paper by Prof. Planer in which he describes his observations of selective light reflection in monotropic cholesteric liquid crystal phase of cholesteryl chloride that he synthesized. Translation by Peter Oelschlaeger, Chemistry Department and Center for Macromolecular Modeling and Material Design and by Hector Cordova Mireles, Department of Physics, both from the California State Polytechnic University at Pomona. Translation was slightly revised by Prof. H.S. Kitzerow, Department of Chemistry from the University of Paderborn in Germany. Reproduced with the permission of Willey-VCH Verlag GmbH & Co. KGaA.
Наведено переклад з німецької оригінальної статті проф. Планера, в якій він описує вибіркове відбивання світла в синтезованій ним монотропній рідкокристалічній фазі хлориду холестеролу. Переклад зроблено П. Оелшлагером та Г. Кордова-Моралесом із Каліфорнійського університету в Помоні та підкореговано проф. Кітзеровим із Падеборнського університету в Німеччині. Публікується з дозволу Willey-VCH Verlag GmbH і Co. KGaA.
Originally published in German in "Mittheilungen aus dem Universit ¨atslaboratorium in Lemberg", Annalen der Chemie und Pharmacie (Annals of Chemistry and Pharmacy), Band CXVIII, Bandes erstes Heft (Issue 1), 25 27, 1861. Copyright Willey-VCH Verlag GmbH & Co. KGaA
en
Інститут фізики конденсованих систем НАН України
Condensed Matter Physics
Rapid Communication
Note about Cholesterol
Замітка про холестерол
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Note about Cholesterol
spellingShingle Note about Cholesterol
Planer, J.
Rapid Communication
title_short Note about Cholesterol
title_full Note about Cholesterol
title_fullStr Note about Cholesterol
title_full_unstemmed Note about Cholesterol
title_sort note about cholesterol
author Planer, J.
author_facet Planer, J.
topic Rapid Communication
topic_facet Rapid Communication
publishDate 2010
language English
container_title Condensed Matter Physics
publisher Інститут фізики конденсованих систем НАН України
format Article
title_alt Замітка про холестерол
description A translation from German of the original paper by Prof. Planer in which he describes his observations of selective light reflection in monotropic cholesteric liquid crystal phase of cholesteryl chloride that he synthesized. Translation by Peter Oelschlaeger, Chemistry Department and Center for Macromolecular Modeling and Material Design and by Hector Cordova Mireles, Department of Physics, both from the California State Polytechnic University at Pomona. Translation was slightly revised by Prof. H.S. Kitzerow, Department of Chemistry from the University of Paderborn in Germany. Reproduced with the permission of Willey-VCH Verlag GmbH & Co. KGaA. Наведено переклад з німецької оригінальної статті проф. Планера, в якій він описує вибіркове відбивання світла в синтезованій ним монотропній рідкокристалічній фазі хлориду холестеролу. Переклад зроблено П. Оелшлагером та Г. Кордова-Моралесом із Каліфорнійського університету в Помоні та підкореговано проф. Кітзеровим із Падеборнського університету в Німеччині. Публікується з дозволу Willey-VCH Verlag GmbH і Co. KGaA.
issn 1607-324X
url https://nasplib.isofts.kiev.ua/handle/123456789/32112
citation_txt Note about Cholesterol / J. Planer // Condensed Matter Physics. — 2010. — Т. 13, № 3. — С. 37001:1-2. — англ.
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fulltext Condensed Matter Physics 2010, Vol. 13, No 3, 37001: 1–2 http://www.icmp.lviv.ua/journal Note about Cholesterol J. Planer Originally published in German in “Mittheilungen aus dem Universitätslaboratorium in Lemberg”∗, Annalen der Chemie und Pharmacie (Annals of Chemistry and Pharmacy), Band CXVIII, Bandes erstes Heft (Issue 1), 25–27, 1861. Copyright Willey-VCH Verlag GmbH & Co. KGaA Translation received June 1, 2010 A translation from German of the original paper by Prof. Planer in which he describes his observations of se- lective light reflection in monotropic cholesteric liquid crystal phase of cholesteryl chloride that he synthesized. Translation by Peter Oelschlaeger, Chemistry Department and Center for Macromolecular Modeling and Mate- rial Design and by Hector Cordova Mireles, Department of Physics, both from the California State Polytechnic University at Pomona. Translation was slightly revised by Prof. H.S. Kitzerow, Department of Chemistry from the University of Paderborn in Germany. Reproduced with the permission of Willey-VCH Verlag GmbH & Co. KGaA. Key words: cholesteryl chloride, monotropic cholesteric liquid crystal phase PACS: 61.30.-v, 64.70.pv, 82.70.Dd The significance that cholesterol gains for the physiologist due to its presence in the animal organism and namely due to its constant appearance in all regressive metamorphoses of animal tissue, moved me a while ago to conduct experiments on this body substance, namely in order to liberate it from its isolated position in the chemical system and to thereby possibly obtain clues for the judgment of its role in the animal body. The guidance for the direction of the experiments for me to conduct seemed to lie in the com- ment by Gerhardt: “After the composition of these hydrocarbons (cholesterol and cholesterone), cholesterol seems to be an alcohol” [original in French] (Traite de chim. org. par Gerhardt III, 739.) ∗At present Lviv, Ukraine. c© J. Planer 37001-1 http://www.icmp.lviv.ua/journal J. Planer Following the advice of Prof. Pebal, I let phosphorus trichloride act on cholesterol, by which I obtained a chlorine compound of cholesterol, which I wanted to use to synthesize other derivatives of the alcohols of analogous compounds of cholesterol. While I was working at these experiments, Berthelot’s note appeared in the Compt. rend. 47: “About several new alcohols”, after which I stopped the continuation of my experiments. However, from the detailed work of Berthelot, which appeared in Ann. ch. phys. 112, 356, I see that the chlorine cholesteryl synthesized in my way is a very different compound than the one that Berthelot obtained by heating hydrochloric acid and cholesterol in a fused tube, which he describes as a non-crystalizable, transparent, resinlike substance, whose chlorine content constantly decreases. This prompts me to call attention to the cholesteryl prepared by me, namely because this compound is quite suitable for the exact determination of the formula of cholesterol and could probably also successfully be used as a starting point for the synthesis of other compounds of this body substance. The action of phosphorous trichloride already proceeds quite actively at room temperature; one obtains a brown, viscous substance, which soon solidifies in crystals and which can easily be purified by squeezing, repeated boiling in water and recrystallization in ether/alcohol. At slow crystalliza- tion from alcohol chlorocholesteryl forms long needle-shaped crystals, at slow crystallization from ether ether/alcohol a crumby crystal paste; those dissolve easily in ether and hardly in wine spirit, contain no crystal water, melt roughly at the boiling point of water; during the cooling process, the molten substance exhibits a lively violet color in incident light, a yellow-green color in transmitted light; when cooling is complete, it adopts a crystalline consistency again. The compound is very hard to decompose; even boiling in concentrated caustic potash does not change it. Since the preliminary analyses of the substance of different preparations yielded numbers, from which the constant composition of the substance emerges, I am presenting these here. The com- bustions were done with chrome acidic lead, for the chlorine determination the substance was destroyed with potash lime. I. 0.439 substance gave 1.287 CO2 and 0.4425 HO. II. 0.448 (of another preparation) 1.308 CO2 and 0.4505 HO. III. 0.540 substance yielded 0.1904 AgCl. IV. 0.613 substance yielded 0.2122 AgCl. From the obtained numbers the calculated numbers for 100 parts are: I. II. III. IV. calculated C 79.95 79.62 – – C32 79.89 H 11.19 11.17 – – H43 11.01 Cl – – 8.71 8.55 Cl 9.09 Замiтка про холестерол Ю. Планер Оригiнал статтi був опублiкований нiмецькою мовою у “Доповiдях з унiверситетських лабораторiй у Лемберзi”, Annalen der Chemie und Pharmacie, том. 118, вип. 1, ст. 25–27, 1861. Переклад з нiмецької оригiнальної статтi проф. Планера, в якiй вiн описує вибiркове вiдбивання свiтла в синтезованiй ним монотропнiй рiдкокристалiчнiй фазi хлориду холистеролу. Переклад зро- блено Пiтером Оелшлагером та Гектором Кордова-Моралесом з Калiфорнiйського унiверситету в Помонi. Переклад був пiдкорегований професором Кiтзеровим з Падеборнського унiверситету в Нiмеччинi. Публiкується з дозволу Willey-VCH Verlag GmbH & Co. KGaA. Ключовi слова: хлорид холестерилу, монотропна холестерична рiдкокристалiчна фаза 37001-2