Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident
The data on the verified cases of mature B-cell neoplasms (chronic lymphocytic leukemia – CLL, B-prolymphocytic leukemia, non-Hodgkin’s lymphoma in leukemization phase and multiple myeloma – MM; 146 cases in total) in the consecutive group of Ukrainian clean-up workers within 10–25 years after Chern...
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| Опубліковано в: : | Experimental Oncology |
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| Дата: | 2011 |
| Автори: | , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/32318 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident / D.F. Gluzman, L.M. Sklyarenko, V.A. Nadgornaya, M.P. Zavelevich // Experimental Oncology. — 2011. — Т. 33, № 1. — С. 47–51. — Біліогр.: 32 назв. — англ. |
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Gluzman, D.F. Sklyarenko, L.M. Nadgornaya, V.A. Zavelevich, M.P. 2012-04-16T20:57:47Z 2012-04-16T20:57:47Z 2011 Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident / D.F. Gluzman, L.M. Sklyarenko, V.A. Nadgornaya, M.P. Zavelevich // Experimental Oncology. — 2011. — Т. 33, № 1. — С. 47–51. — Біліогр.: 32 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/32318 The data on the verified cases of mature B-cell neoplasms (chronic lymphocytic leukemia – CLL, B-prolymphocytic leukemia, non-Hodgkin’s lymphoma in leukemization phase and multiple myeloma – MM; 146 cases in total) in the consecutive group of Ukrainian clean-up workers within 10–25 years after Chernobyl accident are summarized. B-cell neoplasms represent the most prevalent group among all diagnosed neoplasms of hematopoietic and lymphoid tissues in clean-up worker patients under study (49.4%). MM percentage in the patients of Chernobyl clean-up worker group turned out to be significantly higher than in the patients of the general populations studied at the same period. While the percentage of B-CLL is similar in clean-up worker patients and patients of general population, the trend towards younger age of patients with mature B-cell neoplasms in clean-up worker group is evident. The current concepts on the possible association between mature B-cell neoplasms (mainly B-CLL) and radiation exposure are briefly outlined. Only the precise diagnosis of hematopoietic malignancies combining with large-scale analytical epidemiological studies with careful dose assessment and long-term follow-up may represent the basis for resolving the question whether mature B-cell neoplasms may be radiogenic. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident |
| spellingShingle |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident Gluzman, D.F. Sklyarenko, L.M. Nadgornaya, V.A. Zavelevich, M.P. Original contributions |
| title_short |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident |
| title_full |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident |
| title_fullStr |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident |
| title_full_unstemmed |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident |
| title_sort |
mature b-cell neoplasms in chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after chernobyl accident |
| author |
Gluzman, D.F. Sklyarenko, L.M. Nadgornaya, V.A. Zavelevich, M.P. |
| author_facet |
Gluzman, D.F. Sklyarenko, L.M. Nadgornaya, V.A. Zavelevich, M.P. |
| topic |
Original contributions |
| topic_facet |
Original contributions |
| publishDate |
2011 |
| language |
English |
| container_title |
Experimental Oncology |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| format |
Article |
| description |
The data on the verified cases of mature B-cell neoplasms (chronic lymphocytic leukemia – CLL, B-prolymphocytic leukemia, non-Hodgkin’s lymphoma in leukemization phase and multiple myeloma – MM; 146 cases in total) in the consecutive group of Ukrainian clean-up workers within 10–25 years after Chernobyl accident are summarized. B-cell neoplasms represent the most prevalent group among all diagnosed neoplasms of hematopoietic and lymphoid tissues in clean-up worker patients under study (49.4%). MM percentage in the patients of Chernobyl clean-up worker group turned out to be significantly higher than in the patients of the general populations studied at the same period. While the percentage of B-CLL is similar in clean-up worker patients and patients of general population, the trend towards younger age of patients with mature B-cell neoplasms in clean-up worker group is evident. The current concepts on the possible association between mature B-cell neoplasms (mainly B-CLL) and radiation exposure are briefly outlined. Only the precise diagnosis of hematopoietic malignancies combining with large-scale analytical epidemiological studies with careful dose assessment and long-term follow-up may represent the basis for resolving the question whether mature B-cell neoplasms may be radiogenic.
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| issn |
1812-9269 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/32318 |
| citation_txt |
Mature B-CELL neoplasms in Chernobyl clean-up workers of 1986–1987: summary of cytomorphological and immunocytochemical study in 25 years after Chernobyl accident / D.F. Gluzman, L.M. Sklyarenko, V.A. Nadgornaya, M.P. Zavelevich // Experimental Oncology. — 2011. — Т. 33, № 1. — С. 47–51. — Біліогр.: 32 назв. — англ. |
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2025-12-07T21:14:20Z |
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