Ген РС5К9 як причина порушення обміну ліпідів
Proprotein convertase subtilisin/kexin 9 (PCSK9) is a secreted glycoprotein that regulates the degradation of the low-density lipoprotein receptor. Single nucleotide polymorphisms in its gene associate with both hypercholesterolemia and hypocholesterolemia. The identification of PCSK9 regulation by...
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| Published in: | Медична гідрологія та реабілітація |
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| Date: | 2009 |
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| Format: | Article |
| Language: | Ukrainian |
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Інститут фізіології ім. О.О. Богомольця НАН України
2009
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| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/41061 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Ген РС5К9 як причина порушення обміну ліпідів / Ю.М. Панчишин // Медична гідрологія та реабілітація. — 2009. — Т. 7, № 1. — С. 4-7. — Бібліогр.: 35 назв. — укр. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| Summary: | Proprotein convertase subtilisin/kexin 9 (PCSK9) is a secreted glycoprotein that regulates the degradation of the low-density lipoprotein receptor. Single nucleotide polymorphisms in its gene associate with both hypercholesterolemia and hypocholesterolemia. The identification of PCSK9 regulation by these various treatments is important in understanding of the physiological function of this protein, and points to new targets for therapeutic treatments to increase hepatic LDLR numbers.
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| ISSN: | XXXX-0046 |