Значення мікросомального тригліцеридтранспортного протеїну в метаболізмі ліпідів
The microsomal triglyceride transfer protein plays an important role in the folding, assembling and secretion of lipoproteins that contain apoprotein B. Microsomal triglyceride transfer protein is necessary for the assembly and secretion of VLDL and when the protein is not functional, such as in abe...
Saved in:
| Published in: | Медична гідрологія та реабілітація |
|---|---|
| Date: | 2009 |
| Main Authors: | , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
Інститут фізіології ім. О.О. Богомольця НАН України
2009
|
| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/41114 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Значення мікросомального тригліцеридтранспортного протеїну в метаболізмі ліпідів / Ю.М. Панчишин , О.Й. Комариця // Медична гідрологія та реабілітація. — 2009. — Т. 7, № 4. — С. 105-110. — Бібліогр.: 48 назв. — укр. |
Institution
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Summary: | The microsomal triglyceride transfer protein plays an important role in the folding, assembling and secretion of lipoproteins that contain apoprotein B. Microsomal triglyceride transfer protein is necessary for the assembly and secretion of VLDL and when the protein is not functional, such as in abetalipoproteinaemia. Downstream effects resulting from this defect, include very low plasma cholesterol and triglyceride levels, absence of plasma apolipoprotein B and a lipid malabsorption syndrome, leading to lipo-soluble vitamin deficiencies. Deficiencies of these vitamins are known to cause a wide range of clinical effects ranging from blindness to coagulopathy and neuropathy.
|
|---|---|
| ISSN: | XXXX-0046 |