Експресія гена RET в післячорнобильських пухлинах щитовидної залози
The expression of RET gene that encodes a transmembrane receptor with tyrosine kinase activi- ty, was studied on 59 post-Chernobyl thyroid tumors (35 papillary carcinomas and 24 follicular adenomas). It is shown that the majority of tumors, both benign and malignant, exhibits RET expression. The...
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| Datum: | 2008 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | Ukrainian |
| Veröffentlicht: |
Видавничий дім "Академперіодика" НАН України
2008
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| Schlagworte: | |
| Online Zugang: | https://nasplib.isofts.kiev.ua/handle/123456789/4135 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Експресія гена RET в післячорнобильських пухлинах щитовидної залози / Л. Г. Воскобойник, Т.І. Богданова, М.Д. Тронько // Доповіді Національної академії наук України . — 2008. — № 3. — С. 145-148. — Бібліогр.: 14 назв. — укp. |
Institution
Digital Library of Periodicals of National Academy of Sciences of Ukraine| Zusammenfassung: | The expression of RET gene that encodes a transmembrane receptor with tyrosine kinase activi-
ty, was studied on 59 post-Chernobyl thyroid tumors (35 papillary carcinomas and 24 follicular
adenomas). It is shown that the majority of tumors, both benign and malignant, exhibits RET
expression. The presence of gene RET in thyroid tumors was not associated with their hi-
stological structure, invasiveness, tumor’s sizes, and the age and sex of patients. Nevertheless,
the occurrence of RET expression (which is not expressed in normal thyroid cells) in the great
part of post-Chernobyl thyroid tumors suggests a potential role of RET in the development of
thyroid neoplasms, both benign and malignant.
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| ISSN: | 1025-6415 |