Вплив піридину на активність мембранозв’язаних ферментів клітин печінки
Pyridine does not provoke significant changes of the ecto-ATPase and 5′-nucleotidase activities of the plasma membrane of hepatocytes. Mg2+, Ca2+-ATPase activity is not changed under the influence of pyridine too. Pyridine produces the alterations of the Na+, K+-ATPase activity that have biphase cha...
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| Date: | 2008 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
Видавничий дім "Академперіодика" НАН України
2008
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| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/4953 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Вплив піридину на активність мембранозв’язаних ферментів клітин печінки / О.М. Філінська, В.П. Лозовий, С.В. Яблонська, Г.В. Островська, Т.В. Рибальченко, В.О. Зеленюк, В.К. Рибальченко // Доп. НАН України. — 2008. — № 6. — С. 173-177. — Бібліогр.: 14 назв. — укр. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| Summary: | Pyridine does not provoke significant changes of the ecto-ATPase and 5′-nucleotidase activities of the plasma membrane of hepatocytes. Mg2+, Ca2+-ATPase activity is not changed under the influence of pyridine too. Pyridine produces the alterations of the Na+, K+-ATPase activity that have biphase character. A decrease of the enzyme activity is observed at nanomolar and 10−5 M concentrations and disappears at micromolar concentrations. This effect might be caused by features of the pyridine interaction with the membrane lipid matrix.
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| ISSN: | 1025-6415 |