Replication of hepatitis C virus in cell culture
The technique for replicating hepatitis C virus (HCV) in cell culture has been modified and the susceptibility of the cells of various origin to HCV upon their infection with HCV-containing sera has been compared. The viral load on the fifth day post-infection has been assessed by reverse transcript...
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| Дата: | 2009 |
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| Автори: | , , , , , , , |
| Формат: | Стаття |
| Мова: | Англійська |
| Опубліковано: |
Інститут молекулярної біології і генетики НАН України
2009
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| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/5637 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Replication of hepatitis C virus in cell culture / S.L. Rybalko, Yu.I. Porva, I.P. Alekseenko, S.T. Diadiun, M.P. Zavelevych, V.M. Borovykov, L.A. Popova, D.B. Fedorchenko // Біополімери і клітина. — 2009. — Т. 25, № 1. — С. 44-49. — Бібліогр.: 14 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1859992250870661120 |
|---|---|
| author | Rybalko, S.L. Porva, Yu.I. Alekseenko, I.P. Diadiun, S.T. Zavelevych, M.P. Borovykov, V.M. Popova, L.A. Fedorchenko, D.B. |
| author_facet | Rybalko, S.L. Porva, Yu.I. Alekseenko, I.P. Diadiun, S.T. Zavelevych, M.P. Borovykov, V.M. Popova, L.A. Fedorchenko, D.B. |
| citation_txt | Replication of hepatitis C virus in cell culture / S.L. Rybalko, Yu.I. Porva, I.P. Alekseenko, S.T. Diadiun, M.P. Zavelevych, V.M. Borovykov, L.A. Popova, D.B. Fedorchenko // Біополімери і клітина. — 2009. — Т. 25, № 1. — С. 44-49. — Бібліогр.: 14 назв. — англ. |
| collection | DSpace DC |
| description | The technique for replicating hepatitis C virus (HCV) in cell culture has been modified and the susceptibility of the cells of various origin to HCV upon their infection with HCV-containing sera has been compared. The viral load on the fifth day post-infection has been assessed by reverse transcriptase polymerase chain reaction technique. The highest infection and replication efficacy have been found in cells of rat Gasser’s ganglion neurinoma. The peculiar features of the mitotic index and the anomalous forms of the mitosis have been studied in HCV-infected cells. The data presented may be used as a basis for the experimental model of HCV infection in vitro suitable for studying the effects of antiviral drugs on the infection caused by the cytopathogenic variant of HCV.
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| first_indexed | 2025-12-07T16:32:24Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-5637 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 0233-7657 |
| language | English |
| last_indexed | 2025-12-07T16:32:24Z |
| publishDate | 2009 |
| publisher | Інститут молекулярної біології і генетики НАН України |
| record_format | dspace |
| spelling | Rybalko, S.L. Porva, Yu.I. Alekseenko, I.P. Diadiun, S.T. Zavelevych, M.P. Borovykov, V.M. Popova, L.A. Fedorchenko, D.B. 2010-02-01T13:06:44Z 2010-02-01T13:06:44Z 2009 Replication of hepatitis C virus in cell culture / S.L. Rybalko, Yu.I. Porva, I.P. Alekseenko, S.T. Diadiun, M.P. Zavelevych, V.M. Borovykov, L.A. Popova, D.B. Fedorchenko // Біополімери і клітина. — 2009. — Т. 25, № 1. — С. 44-49. — Бібліогр.: 14 назв. — англ. 0233-7657 https://nasplib.isofts.kiev.ua/handle/123456789/5637 578.833.2 : 57.086.83 The technique for replicating hepatitis C virus (HCV) in cell culture has been modified and the susceptibility of the cells of various origin to HCV upon their infection with HCV-containing sera has been compared. The viral load on the fifth day post-infection has been assessed by reverse transcriptase polymerase chain reaction technique. The highest infection and replication efficacy have been found in cells of rat Gasser’s ganglion neurinoma. The peculiar features of the mitotic index and the anomalous forms of the mitosis have been studied in HCV-infected cells. The data presented may be used as a basis for the experimental model of HCV infection in vitro suitable for studying the effects of antiviral drugs on the infection caused by the cytopathogenic variant of HCV. en Інститут молекулярної біології і генетики НАН України Віруси і клітина Replication of hepatitis C virus in cell culture Реплікація вірусу гепатиту C у культурі клітин Репликация вируса гепатита С вкультуре клеток Article published earlier |
| spellingShingle | Replication of hepatitis C virus in cell culture Rybalko, S.L. Porva, Yu.I. Alekseenko, I.P. Diadiun, S.T. Zavelevych, M.P. Borovykov, V.M. Popova, L.A. Fedorchenko, D.B. Віруси і клітина |
| title | Replication of hepatitis C virus in cell culture |
| title_alt | Реплікація вірусу гепатиту C у культурі клітин Репликация вируса гепатита С вкультуре клеток |
| title_full | Replication of hepatitis C virus in cell culture |
| title_fullStr | Replication of hepatitis C virus in cell culture |
| title_full_unstemmed | Replication of hepatitis C virus in cell culture |
| title_short | Replication of hepatitis C virus in cell culture |
| title_sort | replication of hepatitis c virus in cell culture |
| topic | Віруси і клітина |
| topic_facet | Віруси і клітина |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/5637 |
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