Crosstalk between transcription factors in regulation of the human glutathione S-transferase P1 gene expression in Me45 melanoma cells

• Date: 2009
• Main Authors: Slonchak, A.М., Cwieduk, A., Rzerzowska-Wolny, J., Obolenskaya, M.Yu.
• Format: Article
• Language: English
• Published: Інститут молекулярної біології і генетики НАН України 2009
• Subjects: Геноміка, транскриптоміка і протеоміка
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/5659
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Crosstalk between transcription factors in regulation of the human glutathione S-transferase P1 gene expression in Me45 melanoma cells / А.М. Slonchak, А. Cwieduk, J. Rzerzowska-Wolny, M.Yu. Obolenskaya // Біополімери і клітина. — 2009. — Т. 25, № 3. — С. 210–217. — Бібліогр.: 22 назв. — англ.

Aim. The human GSTP1 is a major enzyme of phase II detoxification in the most cell types. Aberrant expression of GSTP1 is associated with carcinogenesis and development of multidrug resistance. The GSTP1 gene expression is regulated at multiple levels including transcriptional, post-transcriptional...