Heterologous cross-expression of oxygenase and glycosyltransferase genes in streptomycetes, producing angucyclic antibiotics

• Published in: Цитология и генетика
• Date: 2009
• Main Authors: Kobylyanskyy, A., Ostash, B., Fedorenko V.
• Format: Article
• Language: English
• Published: Інститут клітинної біології та генетичної інженерії НАН України 2009
• Subjects: Оригинальные работы
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/66645
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Heterologous cross-expression of oxygenase and glycosyltransferase genes in streptomycetes, producing angucyclic antibiotics / A. Kobylyanskyy, B. Ostash, V. Fedorenko // Цитология и генетика. — 2009. — Т. 43, № 3. — С. 55-62. — Бібліогр.: 15 назв. — англ.

The heterologous expression of oxygenase genes urdM, ovmOIII, lanM2, lndZ5 and glycosyltransferase gene urdGT2 in different angucycline producers of genus Streptomyces has been carried out. The introduction of genes urdM, lanM2 and urdGT2 results in the accumulation of new glycosylated compounds in...