Investigations of genotoxic activity of antimicrobial/antiviral agent FS-1 in human lymphocytes and tumor cell

• Published in: Цитология и генетика
• Date: 2011
• Main Authors: Nersesyan, A., Ilin, A., Kulmanov, M.
• Format: Article
• Language: English
• Published: Інститут клітинної біології та генетичної інженерії НАН України 2011
• Subjects: Оригинальные работы
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/66827
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Investigations of genotoxic activity of antimicrobial/antiviral agent FS-1 in human lymphocytes and tumor cell / A. Nersesyan, A. Ilin, M. Kulmanov // Цитология и генетика. — 2011. — Т. 45, № 2. — С. 10-15. — Бібліогр.: 15 назв. — англ.

A very promising antiviral and antimicrobial agent FS-1 was studied for its ability to induce DNA damage and micronuclei in human tumor cell lines HeLa and Caco-2 at concentrations of 200, 500 and 1000 mg/ml without exogenous metabolic activation. The compound was additionally tested for DNA damagin...