Microwave assisted synthesis of pyrimido[4,5-d]pyrimidine derivatives in dry media

Pyrimido[4,5-d]pyrimidine derivatives were synthesized by using an efficient, facile and solvent-free procedure. Here, a non-conventional synthetic procedure has been developed where solid support of alumina is used as energy transfer medium under microwave irradiation (MWI) which devoids hazards of...

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Datum:2009
Hauptverfasser: Kategaonkar, A.H., Sadaphal, S.A., Shelke, K.F., Shingate, B.B., Shingare, M.S.
Format: Artikel
Sprache:English
Veröffentlicht: Інститут молекулярної біології і генетики НАН України 2009
Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/7368
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Microwave assisted synthesis of pyrimido[4,5-d]pyrimidine derivatives in dry media / A.H. Kategaonkar, S.A. Sadaphal, K.F. Shelke, B.B. Shingate, M.S. Shingare // Ukrainica Bioorganica Acta. — 2009. — Т. 7, № 1. — С. 3-7. — Бібліогр.: 19 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Zusammenfassung:Pyrimido[4,5-d]pyrimidine derivatives were synthesized by using an efficient, facile and solvent-free procedure. Here, a non-conventional synthetic procedure has been developed where solid support of alumina is used as energy transfer medium under microwave irradiation (MWI) which devoids hazards of solution phase reactions. The reaction time has been brought down from minutes to seconds with improved yield as compared to reported method.