Експериментальні дослідження гістологічних зрізень епідермісу людської шкіри

• Дата: 2024
• Автори: Павлов, В.C., Ровіра, Хурадо Рональд Умберто, Заболотна, Н.І., Холін, В.В., Никифорова, Л.Є., Комарова, О.С.
• Формат: Стаття
• Мова: Ukrainian
• Опубліковано: Vinnytsia National Technical University 2024
• Теми: оптичні вимірювання; метод Монте-Карло; оптично анізотропні біотканини; медична діагностика.
• Онлайн доступ: https://oeipt.vntu.edu.ua/index.php/oeipt/article/view/704
• Назва журналу: Optoelectronic Information-Power Technologies

In the article developed as a result of the analysis of the obtained 2D distributions of the anisotropy parameters of the epidermis samples, only linear birefringence was found, the value of which changes in the plane of the section according to the thickness and density of the tissue fibers. Correspondingly, along the same fiber directions, the orientation of the birefringence axis changes smoothly (in the area of ​​the tissue without pathology). For the affected areas of the tissue, the birefringence value is more homogeneous in the cross-section, and in the areas with visible severe damage it is minimal. The change in the orientation of in areas with a small and clearly visible lesion is chaotic. Thus, melanoma destroys epidermal cells so much that they become practically isotropic. Healthy tissue samples have a natural orientational order.