Цілеспрямований синтез 4-о-арил- і 4-N-алкіл/арилхіназолінів для дослідження JNK-кіназної активності
To study the JNK-kinase activity of quinazoline derivatives a series of 4-O-aryl- and 4-N-alkylquinazolines have been synthesized in standard condition of nucleophilic substitution of 4-chloroquinazolines in the presence of potassium carbonate. 4-Chloroquinazolines have been obtained by the reaction...
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| Date: | 2014 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
National University of Pharmacy
2014
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/ophcj.14.792 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |