Синтез 3-арил-3-трифторометил-2,3-дигідро-1Н-піролізин-1-онів

Aim. To develop the efficient method for the synthesis of 3-aryl-3-trifluoromethyl-2,3-dihydro-1H-pyrrolizin-1-ones as promising scaffolds in design of bioactive compounds.Results and discussion. It has been shown that condensation of 3-amino-3-aryl-4,4,4-trifluorobutanoic acid methyl esters with 2,...

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Bibliographic Details
Date:2019
Main Authors: Melnykov, S. V., Tkachuk, V. M., Grozav, A. M., Gillaizeau, I., Sukach, V. A.
Format: Article
Language:Ukrainian
Published: National University of Pharmacy 2019
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Online Access:https://ophcj.nuph.edu.ua/article/view/ophcj.19.961
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Journal Title:Journal of Organic and Pharmaceutical Chemistry

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Journal of Organic and Pharmaceutical Chemistry