Синтез та алкілування 5-арил-1,2-дигідро-3H-1,2,4-триазол-3-тіонів

• Date: 2021
• Main Authors: Dovbnya, Dmytro V., Kaplaushenko, Andrii G., Korzhova, Alla S.
• Format: Article
• Language: Ukrainian
• Published: National University of Pharmacy 2021
• Subjects: 1,2,4-триазоли; 5-(2,4- та 3,4-диметоксифеніл)-3H-1,2,4-триазол-3-тіони; реакції алкілування; 547.79’286.2.057
• Online Access: https://ophcj.nuph.edu.ua/article/view/188135
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

5-R-1,2,4-triazole-3-thiones and their derivatives are easy to obtain; they have low toxicity and a broad spectrum of the biological activity. It makes this class of heterocyclic compounds promising for creating potential drugs. Aim. To develop the preparative methods for the synthesis of 5-aryl-1,2...