Естери та аміди 3-R-2,8-діоксо-7,8-дигідро-2Н-піроло[1,2-а][1,2,4]триазино[2,3-с]-хіназолін-5а(6Н)-карбонових(-пропанових) кислот: синтез та біологічна активність
It is known that carboxyl groups bonded to aryl or hetaryl moieties play a role of the “pharmacophore” fragment in most NSAID molecules. It should be mentioned that the carboxyl group may cause the appearance of toxic effects and is characterized by unsatisfactory pharmacokinetic properties. The str...
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| Date: | 2020 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2020
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/ophcj.20.192826 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |