Синтез цис- та транс-3-(4-гідроксифеніл)циклобутанкарбонових кислот та дослідження їх похідних як лігандів рецептора GPR-40

Aim. To synthesize cis- and trans-isomers of 3-(4-hydroxyphenyl)cyclobutanecarboxylic acid and evaluate the biological activity of their derivatives against GPR-40.Results and discussion. Cis- and trans-isomers of 3-(4-hydroxyphenyl)cyclobutanecarboxylic acid were synthesized. The derivatives of thi...

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Bibliographic Details
Date:2020
Main Authors: Feskov, I. O., Kondratov, I. S., Kuchkovska, Yu. O., Naumchyk, V. S., Onopchenko, O. V., Grygorenko, O. O.
Format: Article
Language:Ukrainian
Published: National University of Pharmacy 2020
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Online Access:https://ophcj.nuph.edu.ua/article/view/ophcj.20.210383
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Journal Title:Journal of Organic and Pharmaceutical Chemistry

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Journal of Organic and Pharmaceutical Chemistry