N-Дифлуорометиліндазоли

• Published in: Журнал органічної та фармацевтичної хімії
• Date: 2022
• Volume: 20
• Issue: 3
• Pages: 3-11
• ISSN: 2518-1548
• Author Affiliations: Kirill I. Petko — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Andrey A. Filatov — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Enamine Ltd.
• Main Authors: Petko, Kirill I., Filatov, Andrey A.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2022
• Subjects: індазоли; N-дифлуорометилювання; розділення ізомерів
• Online Access: https://ophcj.nuph.edu.ua/article/view/265823
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

Aim. To study the possibility of the N-difluoromethylation and separation of 1-difluoromethyl and 2-difluoromethyl isomers of C-substituted indazoles, as well as some possibilities of functionalization of such molecules.Results and discussion. The N-difluoromethylation of indazole derivatives contai...