Пошук потенційних інгібіторів SARS-CoV-2 за допомогою in silico методів

• Date: 2023
• Main Authors: Suleiman, Marharyta M., Fedosov, Andrii I., Mohapatra, Ranjan K., Sych, Irina A., Grinevich, Lina O., Kobzar, Nataliia P., Yaremenko, Vitaliy D., Perekhoda, Lina O.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2023
• Subjects: COVID-19 вірус; криніпелін А; гнучкий молекулярний докінг; інгібітор SARS-COV-2
• Online Access: https://ophcj.nuph.edu.ua/article/view/276412
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

Aim. Using in silico technologies to search for potential SARS-CoV-2 inhibitors among novel tetracyclic ring systems, which are the common core of Crinipellin.Materials and methods. The study object was new compounds previously synthesized via oxidative dearomatization of Crinipellin A. The method o...