Синтез нового ряду хромонів на основі формілтіазолів

A preparative approach to thiazole-containing chromone derivatives has been developed by modifying the corresponding aldehydes with their further transformation into propenone derivatives, and finally introducing them into the Algar-Flynn-Oyamada reaction. Several methods for obtaining propenones ha...

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Datum:2023
Hauptverfasser: Tarasenko, Dmytro O., Chumak, Andriy Y., Kolomoitsev, Oleksii O., Kotliar, Volodymyr M., Roshal, Alexander D.
Format: Artikel
Sprache:English
Veröffentlicht: National University of Pharmacy 2023
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Online Zugang:https://ophcj.nuph.edu.ua/article/view/292844
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Назва журналу:Journal of Organic and Pharmaceutical Chemistry

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Journal of Organic and Pharmaceutical Chemistry
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Zusammenfassung:A preparative approach to thiazole-containing chromone derivatives has been developed by modifying the corresponding aldehydes with their further transformation into propenone derivatives, and finally introducing them into the Algar-Flynn-Oyamada reaction. Several methods for obtaining propenones have been analyzed, and the most effective and practically convenient one has been found. The thiazole-containing analogs of chromones obtained have a great potential as probes for a wide range of studies.