Синтез функціоналізованих диметилфосфіноїл циклопропанів і циклобутанів

• Published in: Журнал органічної та фармацевтичної хімії
• Date: 2023
• Volume: 21
• Issue: 4
• Pages: 36-42
• ISSN: 2518-1548
• Author Affiliations: Anastasiia M. Aleksandrova — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Alona S. Cherednichenko — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Yuliya V. Rassukana
• Main Authors: Aleksandrova, Anastasiia M., Cherednichenko, Alona S., Rassukana, Yuliya V.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2023
• Subjects: диметилфосфіноксиди; циклопропан; циклобутан; аміни; карбонові кислоти
• Online Access: https://ophcj.nuph.edu.ua/article/view/299237
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic procedures for obtaining nitriles, amines and...