5-Трифлуорометоксизаміщена нікотинова кислота, нікотинамід і споріднені сполуки

• Date: 2024
• Main Authors: Sokolenko, Taras M., Yagupolskii, Yurii L.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2024
• Subjects: нікотинова кислота; нікотинамід; трифлуорометоксигрупа; стибій трифлуорид; флуорування
• Online Access: https://ophcj.nuph.edu.ua/article/view/302435
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

A practical and convenient method for synthesizing nicotinic acid and nicotinamide with the trifluoromethoxy group in position 5 of the ring has been developed. A series of related compounds, for example, nicotinic aldehyde and nicotinic alcohol, have been synthesized. It has been shown that 3-bromo...