Кількісне визначення етонію ферментативним кінетико-спектрофотометричним методом

The use of the cholinesterase enzyme as a component of the analytical system has made it possible to develop a new kinetic-spectrophotometric method, which is alternative to the pharmacopoeial method, for determining the quaternary ammonium salt – ethonium in the substance and a dosage form. This me...

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Збережено в:
Бібліографічні деталі
Дата:2024
Автори: Blazheyevskiy, Mykola Ye., Kovalska, Olena V.
Формат: Стаття
Мова:English
Опубліковано: National University of Pharmacy 2024
Теми:
Онлайн доступ:https://ophcj.nuph.edu.ua/article/view/304120
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Назва журналу:Journal of Organic and Pharmaceutical Chemistry

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Journal of Organic and Pharmaceutical Chemistry
Опис
Резюме:The use of the cholinesterase enzyme as a component of the analytical system has made it possible to develop a new kinetic-spectrophotometric method, which is alternative to the pharmacopoeial method, for determining the quaternary ammonium salt – ethonium in the substance and a dosage form. This method is characterized by high sensitivity and specificity, and is relatively cheap. The relative standard deviation of the procedure does not exceed 2.7 %, and the limit of quantification is 17 ng mL–1.