Кількісне визначення етонію ферментативним кінетико-спектрофотометричним методом
The use of the cholinesterase enzyme as a component of the analytical system has made it possible to develop a new kinetic-spectrophotometric method, which is alternative to the pharmacopoeial method, for determining the quaternary ammonium salt – ethonium in the substance and a dosage form. This me...
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| Date: | 2024 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2024
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/304120 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |
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Journal of Organic and Pharmaceutical Chemistry| Summary: | The use of the cholinesterase enzyme as a component of the analytical system has made it possible to develop a new kinetic-spectrophotometric method, which is alternative to the pharmacopoeial method, for determining the quaternary ammonium salt – ethonium in the substance and a dosage form. This method is characterized by high sensitivity and specificity, and is relatively cheap. The relative standard deviation of the procedure does not exceed 2.7 %, and the limit of quantification is 17 ng mL–1. |
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