Масштабований синтез похідних 2-азабіцикло[2.1.1]гексан-1-карбоксилату (2,4-метанопроліну) – перспективних біциклічних аналогів проліну
An optimized approach towards 4-substituted 2,4-methanoproline derivatives is reported. Careful selection of the starting materials and optimized isolation procedure provided easy access to a key bicyclic building block in a preparative yield of 32% over five laboratory steps of up to 0.7 kg. Furthe...
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| Date: | 2024 |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2024
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/314843 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |