Перегляд синтезу орто-карборанів: успіх для монозаміщених ацетиленів у присутності солей срібла

• Published in: Журнал органічної та фармацевтичної хімії
• Date: 2024
• Volume: 22
• Issue: 3
• Pages: 38-45
• ISSN: 2518-1548
• Author Affiliations: Oleh V. Svaliavyn — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Enamine Ltd.; Artem M. Mishchenko — Enamine Ltd.; Yulian L. Lishchenko — Enamine Ltd.; Andrey P. Mityuk — Enamine Ltd.; Taras Shevchenko National University of Kyiv; Alona S. Cherednichenko — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Nataliya A. Shtil — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Enamine Ltd.; Volodymyr V. Turcheniuk — Enamine Ltd.; Radomyr V. Smaliy — Enamine Ltd.; National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”; Yuliya V. Rassukana — Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; Olexandr Ye. Pashenko — Enamine Ltd; Taras Shevchenko National University of Kyiv; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine
• Main Authors: Svaliavyn, Oleh V., Mishchenko, Artem M., Lishchenko, Yulian L., Mityuk, Andrey P., Cherednichenko, Alona S., Shtil, Nataliya A., Turcheniuk, Volodymyr V., Smaliy, Radomyr V., Rassukana, Yuliya V., Pashenko, Olexandr Ye.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2024
• Subjects: орто-карборани; декаборан; ацетилени; срібло; синтез
• Online Access: https://ophcj.nuph.edu.ua/article/view/316200
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

The study shows that traditional methods for synthesizing ortho-carboranes from nido-B10H14 and its complexes (B10H12L2) using donor- and acceptor-disubstituted acetylenes yielding low efficiencies (yields 0 - 12%). Attempts to improve yields with ionic liquids and silver salts as catalysts were uns...