Переосмислення компонентів високотемпературних полімерів: масштабований синтез і de novo шляхи до структурно різноманітних прекурсорів

• Date: 2024
• Main Authors: Kurganov, Roman M., Svaliavyn, Oleh V., Pashchenko, Yevgen O., Savchenko, Denis O., Rozhenko, Alexander B., Ryabukhin, Serhiy V., Volochnyuk, Dmitriy M.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2024
• Subjects: термостійкі полімери; мономери; олігомери; затверджувачі; триазин; фталонітрил; боросилан; діамін; синтез
• Online Access: https://ophcj.nuph.edu.ua/article/view/317091
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

Developing efficient and scalable synthetic protocols for key polymer precursors is crucial to advancing high-performance materials designed to withstand severe thermal environments. In this article, we report on the development of solid, high-yield methods for preparing structurally diverse building blocks, including s-triazine derivatives, phenyl-borosilane alkynyl oligomers, phthalonitrile-based monomers, and novel diamine curing agents on multi-gram to multi-hundred-gram scales. These carefully optimized procedures use readily available starting materials, mild conditions, and well-known synthetic transformations, thus addressing the longstanding challenges associated with their practical upscaling. The resulting library of monomers and oligomers offers a broad range of reactive functional groups (e.g., nitriles, alkynes, borosilane motifs), enabling future combinatorial-like strategies for the formation of advanced co-polymers with enhanced thermal stability, mechanical strength, and tunable properties suitable for high-temperature applications.