Розробка багатостадійної технології промислового синтезу АФІ левосимендану та енантіомерного розділення проміжних продуктів
A method for obtaining Levosimendan suitable for industrial application has been developed. Two literature routes for the synthesis have been evaluated. It has been found that the use of enantiopure (R)-2-chloropropionyl chloride in the initial step is ineffective due to racemization at the stage of...
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| Date: | 2025 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2025
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/322447 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |