Дослідження антибактеріальної дії екстракту зимолюбки зонтичної

• Date: 2024
• Main Authors: Kovregin, Oleksiy V., Osolodchenko, Tetyana P., Vladymyrova, Inna M.
• Format: Article
• Language: English
• Published: National University of Pharmacy 2024
• Subjects: зимолюбка зонтична; рідкий екстракт; антимікробна дія
• Online Access: https://ophcj.nuph.edu.ua/article/view/324652
• Journal Title: Journal of Organic and Pharmaceutical Chemistry

The article presents the studies on the antimicrobial effect of the umbellate wintergreen herb extract. The study object was the umbellate wintergreen herb extract obtained with 50% ethyl alcohol. The sensitivity of microbial strains to the umbellate wintergreen extract was determined by the well diffusion method in Mueller Hinton agar. Five test strains were used as test cultures: Staphylococcus aureus ATCC 6538 gram-positive microorganisms, Bacillus subtilis ATCC 6633 spore culture, gram-negative Proteus vulgaris ATCC 4636, Escherichia coli ATCC 25922, and Pseudomonas aeruginosa ATCC 9027. The antifungal effect was determined against Candida albicans ATCC 885-653. The antibacterial activity of the test substances was assessed by the diameter of the growth inhibition zones. It was found that the extract of the umbellate wintergreen herb exhibited antibacterial properties against test microorganisms where the diameters of the growth inhibition zones were at the level of 20-28 mm. The antibacterial effect of the umbellate wintergreen herb extract was also determined against such clinical strains of microorganisms as Staphylococcus aureus 124, Enterococcus faecalis 42, Pseudomonas aeruginosa 18, Klebsiella pneumoniae 64, Candida albicans 69. The growth inhibition zones were within 19-24 mm.