Удосконалений синтез ROCKYPhos та його застосування для асиметричного гідрування похідних дигідроізохіноліну
An optimized approach to the multigram synthesis of [(1R,2R,3S)-(+)-1,2-dimethyl-2,3-bis(diphenylphosphinomethyl)cyclopentyl]methanol (ROCKYPhos, CatASium I®), a camphor-derived chiral diphosphine ligand, has been developed. The key improvement in the synthetic scheme involved the oxidative cleavage...
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| Date: | 2026 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
National University of Pharmacy
2026
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| Subjects: | |
| Online Access: | https://ophcj.nuph.edu.ua/article/view/353838 |
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| Journal Title: | Journal of Organic and Pharmaceutical Chemistry |