Криоконсервированные клетки фетальной печени, заключенные в макропористые носители, способствуют восстановлению функций печени после поражения 2-ацетиламинуфлуореном

The effect of cryopreserved fetal liver cells immobilized in macroporous alginate scaffolds on liver injury degree in rats with model of liver failure developed by administration of 2-acetylaminofluorene with subsequent partial hepatectomy. It was shown that immobilized fetal liver cells accelerated...

Повний опис

Збережено в:
Бібліографічні деталі
Дата:2024
Автори: Gritsay, D. V., Lebedinskiy, A. S., Ochenashko, O. V., Petrenko, Yu. A.
Формат: Стаття
Мова:English
Опубліковано: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2024
Теми:
Онлайн доступ:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/101
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Назва журналу:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
Опис
Резюме:The effect of cryopreserved fetal liver cells immobilized in macroporous alginate scaffolds on liver injury degree in rats with model of liver failure developed by administration of 2-acetylaminofluorene with subsequent partial hepatectomy. It was shown that immobilized fetal liver cells accelerated recovery of spesific hepatic indices: serum albumin, total bilirubin content, aminotransferase activity. The results of this work indicate the positive effect of fetal liver cells seeded in macroporous scaffolds on course of liver failure and argue the availability of this approach for liver failure treatment.