Кинетические характеристики Са2+-АТФазы эритроцитов в присутствии ПЭО-1500

• Datum: 2003
• Hauptverfasser: Zemlyanskikh, N. G., Babijchuk, L. A., Nikolchenko, A. Yu., Tyagileva, V. P.
• Format: Artikel
• Sprache: English
• Veröffentlicht: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2003
• Schlagworte: еритроцити; Са2 -АТФаза; кріопротектор; поліетиленоксид
• Online Zugang: https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1075
• Назва журналу: Problems of Cryobiology and Cryomedicine

In the work it has been established, that the exocellular cryoprotectant PEO-1500 inhibits the activity of Ca2+-ATPase of erythrocytes. Kinetic analysis showed that the inhibition of enzyme activity was related to the Vmax alteration, but not to Km for catalytic center with a low affinity of Ca2+-AT...