Влияние криоконсервированного экстракта плаценты на интенсивность ПОЛ и содержание гидроперекисей липидов в тканях крыс в норме и после общего острого охлаждения

• Date: 2005
• Main Authors: Prokopyuk, O. S., Cheremskoy, A. K., Nikitchenko, Yu. V., Chizhevsky, V. V.
• Format: Article
• Language: English
• Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2005
• Subjects: спонтанне перекисне окислення; аскорбат-індуцироване окислення; гідроперекиси ліпідів; кріоконсервований екстракт плаценти; загальне гостре охолодження
• Online Access: https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1219
• Journal Title: Problems of Cryobiology and Cryomedicine

Effect of cryopreserved placenta extract on lipid peroxidation (LPO) intensity and lipid hydroperoxide content in Wistar line rats’ blood serum and liver, heart homogenates under normal conditions and following general acute cooling was studied. General acute cooling of animals was found to increase the LPO intensity as well as lipid hydroperoxide content in rat liver, heart tissues and blood serum. Introduction of cryopreserved placenta extract prevents LPO activation in all studied tissues of experimental animals and we believe this testifies to the activation of biochemical adaptation mechanisms, compensating cold-caused disorders.