Вплив різних режимів охолодження (краніоцеребральної і імерсійної гіпотермії, поверхневих ритмічних і екстремальних холодових впливів) на лейкоцитарні показники крові щурів

• Date: 2019
• Main Author: Lomako, Victoria V.
• Format: Article
• Language: English
• Published: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2019
• Subjects: Краніоцеребральна гіпотермія; імерсійна гіпотермія; ритмічні холодові впливи; екстремальні холодові впливи; лейкоцити; інтегральні лейкоцитарні індекси; щури
• Online Access: https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1456
• Journal Title: Problems of Cryobiology and Cryomedicine

A comparative analysis of leukocyte types number in rat blood smears at the craniocerebral (CCH 32°C) and  immersion  (IH  27°C)  hypothermia,  surface rhythmic  cold  exposures  (RCEs  5°C)  and  whole  body  cryostimulation (WBC -120°C), as well as in 24 hrs revealed the leukocytosis (at IH and 24 hrs after CCH and IH), leukopenia (at  CCH, RCEs and 24 hrs after WBC), lymphopenia, an increase in band and segmented cells (under all conditions except IH) and eosinophils (only at CCH and 24 hrs after WBC). Plasmatic cells (except WBC), polychromatophilic and immature cells (immediately and in 24 hrs after CCH and IH), cytoplasm plasmatization in some leukocytes (24 hrs after CCH and IH) were observed. Leukocyte indices showed the immunoreactivity disorder, decreased allergization, activation of cell immunity, nonspecific cell protection and inflammation (under all conditions, except IH), as well as microphages (at WBC and 24 hrs after CCH and IH), an effector component of immunity (at CCH, RCEs and 24 hrs after WBC), immediate type hypersensitivity responses (except at CCH and 24 hrs after WBC). The nuclear shift index was increased (except RCEs and WBC). The adaptation index was raised only at IH. Probl Cryobiol Cryomed 2018; 28(4): 293-310