ВлиÑние амфифильных вещеÑтв на гипертоничеÑкий гемолиз Ñритроцитов, модифицированных температурой 49°С
The effect of thermal pre-treatment of human and bovine erythrocytes on their sensitivity to hypertonic stress (4.0 mol/l NaCl) at 37 and0°Cwas studied. It has been shown that cell incubation at49°C, causing spectrin denaturation, decreases the level of human erythrocyte hypertonic damage and does...
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| Date: | 2011 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine
2011
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| Subjects: | |
| Online Access: | https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/169 |
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| Journal Title: | Problems of Cryobiology and Cryomedicine |
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Problems of Cryobiology and Cryomedicine| Summary: | The effect of thermal pre-treatment of human and bovine erythrocytes on their sensitivity to hypertonic stress (4.0 mol/l NaCl) at 37 and0°Cwas studied. It has been shown that cell incubation at49°C, causing spectrin denaturation, decreases the level of human erythrocyte hypertonic damage and does not affect the integrity of bovine erythrocytes at37°C. Hypertonic hemolysis of modified mammalian erythrocytes does not change at0°C. Cytoskeletal spectrin denaturation of bovine and human erythrocytes results in reduction of antihemolytic activity of amphiphilic substances (sodium decyl sulfate, dodecyl-β,D-maltoside, trifluoroperazine) at 37 and0°C. |
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