Влияние амфифильных веществ на гипертонический гемолиз эритроцитов, модифицированных температурой 49°С

The effect of thermal pre-treatment of human and bovine erythrocytes on their sensitivity to hypertonic stress (4.0 mol/l NaCl) at 37 and0°Cwas studied. It has been shown that cell incubation at49°C, causing spectrin denaturation, decreases the level of human erythrocyte hypertonic damage and does...

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Збережено в:
Бібліографічні деталі
Дата:2011
Автори: Pisarenko, N. A., Shpakova, N. M.
Формат: Стаття
Мова:English
Опубліковано: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2011
Теми:
Онлайн доступ:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/169
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Назва журналу:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
Опис
Резюме:The effect of thermal pre-treatment of human and bovine erythrocytes on their sensitivity to hypertonic stress (4.0 mol/l NaCl) at 37 and0°Cwas studied. It has been shown that cell incubation at49°C, causing spectrin denaturation, decreases the level of human erythrocyte hypertonic damage and does not affect the integrity of bovine erythrocytes at37°C. Hypertonic hemolysis of modified mammalian erythrocytes does not change at0°C. Cytoskeletal spectrin denaturation of bovine and human erythrocytes results in reduction of antihemolytic activity of amphiphilic substances (sodium decyl sulfate, dodecyl-β,D-maltoside, trifluoroperazine) at 37 and0°C.