Адсорбція та хімічні перетворення лідокаїну на поверхні високодисперсного кремнезему

• Datum: 2010
• Hauptverfasser: Kulyk, T. V., Dudik, O. O., Palyanytsya, B. B., Barvinchenko, V. M.
• Format: Artikel
• Sprache: Ukrainisch
• Veröffentlicht: Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine 2010
• Online Zugang: https://www.cpts.com.ua/index.php/cpts/article/view/22
• Назва журналу: Chemistry, Physics and Technology of Surface

It has been found that the highest adsorption of lidocaine on silica surface is observed at рН~8.1 similar to рКа of lidocaine (рК=7.9), that is in a region of рН optimal for realization of maximum biological effect. The interaction of lidocaine with fumed silica surface has been studied by the temp...