Исследование влияния низкомолекулярных криопротекторов на дыхательную цепь митохондрий методом ЭПР спинового зонда

Effect of low molecular cryoprotectants, glycerol, 1,2-propane diol and dimethylsulfoxide with concentrations up to 30% on activity of respiratory chain of rat liver mitochondria membranes has been studied by spin probe EPR. It has been established that lowmolecular cryoprotective substances induce...

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Bibliographische Detailangaben
Datum:2009
1. Verfasser: Nardid, O. A.
Format: Artikel
Sprache:English
Veröffentlicht: Publishing House ‘Akademperiodyka’ of the National Academy of Sciences of Ukraine; Institute for Problems of Cryobiology and Cryomedicine 2009
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Online Zugang:https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/272
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Назва журналу:Problems of Cryobiology and Cryomedicine

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Problems of Cryobiology and Cryomedicine
Beschreibung
Zusammenfassung:Effect of low molecular cryoprotectants, glycerol, 1,2-propane diol and dimethylsulfoxide with concentrations up to 30% on activity of respiratory chain of rat liver mitochondria membranes has been studied by spin probe EPR. It has been established that lowmolecular cryoprotective substances induce inhibition of isolated organelles’ respiratory chain. It has been shown that inhibition rate of spin probe reduction and mitochondria respiration as a part of hepatocytes is lower at the same concentrations, if compared with isolated mitochondria.