Кремнеземні носії для контрольованого вивільнення активної речовини
Immobilization of sodium diclofenac via adsorption and impregnation from alcohol solution on unmodified and modified silicas was carried out. Influence of chemical modification of silica surface on active substance release rate was shown. Presence of methylsilyl groups in silica surface layer signif...
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| Date: | 2008 |
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| Main Authors: | , , |
| Format: | Article |
| Language: | Ukrainian |
| Published: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2008
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| Online Access: | https://surfacezbir.com.ua/index.php/surface/article/view/287 |
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| Journal Title: | Surface |
| Download file: |  |
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Surface| Summary: | Immobilization of sodium diclofenac via adsorption and impregnation from alcohol solution on unmodified and modified silicas was carried out. Influence of chemical modification of silica surface on active substance release rate was shown. Presence of methylsilyl groups in silica surface layer significantly decrease the rate of sodium diclofenac from release silica matrix into water or buffer solution. |
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