Вплив полівінілпіролідону і поліоксіетилену на адсорбцію білків на поверхні нанокремнезему

The paper studies the effect of modification of the surface of amorphous nonporous high-disperse nano-sized silica (nanosilica) with aprotonic watersoluble polymers – polyvinylpyrrolidone (PVP, M » 12000) and polyethylene oxide (PEO, М = 20000) – o...

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Bibliographic Details
Date:2009
Main Authors: Vasilenko, A. P., Guzenko, N. V., Маlysheva, M. L., Voronin, E. F.
Format: Article
Language:Russian
Published: Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine 2009
Online Access:https://surfacezbir.com.ua/index.php/surface/article/view/334
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Journal Title:Surface
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Summary:The paper studies the effect of modification of the surface of amorphous nonporous high-disperse nano-sized silica (nanosilica) with aprotonic watersoluble polymers – polyvinylpyrrolidone (PVP, M » 12000) and polyethylene oxide (PEO, М = 20000) – on its ability of proteins adsorption – gelatine and bovine serum albumin (BSA). The presence of aprotonic watersoluble polymers (PVP, PEO) in a solution was found to diminish the value of adsorption of these proteins on silica surface both at stepwise and simultaneous adsorbate introduction into a suspension. It was established that PVP and PEO was able to displace previously adsorbed protein molecules from the surface layer.