Адсорбція доксорубіцину пірогенним кремнеземом та нанокомпозитами магнетит/силоксан
A technique has been developed for immobilization of the cytostatic drug doxorubicin on the surface of magnetite nanoparticles modified with biocompatible siloxane coating and fumed silica. The processes of adsorption/desorption of doxorubicin at given surfaces were studied, high adsorption activity...
Збережено в:
| Дата: | 2015 |
|---|---|
| Автори: | , , , |
| Формат: | Стаття |
| Мова: | Українська |
| Опубліковано: |
Chuiko Institute of Surface Chemistry National Academy of Sciences of Ukraine
2015
|
| Теми: | |
| Онлайн доступ: | https://www.cpts.com.ua/index.php/cpts/article/view/352 |
| Теги: |
Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|
| Назва журналу: | Chemistry, Physics and Technology of Surface |
Репозитарії
Chemistry, Physics and Technology of Surface| Резюме: | A technique has been developed for immobilization of the cytostatic drug doxorubicin on the surface of magnetite nanoparticles modified with biocompatible siloxane coating and fumed silica. The processes of adsorption/desorption of doxorubicin at given surfaces were studied, high adsorption activity of siloxane surface of nanocomposites was determined with respect to doxorubicin. New nanocomposites magnetite/siloxane/doxorubicin synthesized may be promising for use in oncology, in creating the remedies for targeted delivery of drugs and as adsorption materials for intracorporal and extracorporal detoxification of the organism. |
|---|---|
| DOI: | 10.15407/hftp06.04.481 |